Title:
SKIN WHITENING COMPOSITION COMPRISING D-TYROSINE OR PEPTIDE COMPRISING SAME
Document Type and Number:
WIPO Patent Application WO/2019/059634
Kind Code:
A1
Abstract:
The present invention relates to a skin whitening composition comprising D-tyrosine or a peptide comprising the same. More specifically, the present invention relates to a skin whitening cosmetic composition comprising D-tyrosine or a peptide comprising the same, or a salt thereof; a pharmaceutical composition; a functional health food composition; a quasi-drug composition; and a composition for inhibiting melanin synthesis. D-tyrosine or a peptide comprising the same inhibits melanin synthesis and reduces the amount of melanin produced by L-tyrosine, α-MSH or UV rays, which is a major factor causing melanin synthesis. Since D-tyrosine or the peptide comprising the same does not exhibit toxicity to skin cells, the composition of the present invention comprising D-tyrosine or the peptide can be used safely and effectively in skin whitening.
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Inventors:
OH EOK-SOO (KR)
PARK JISU (KR)
JUNG HYEJUNG (KR)
PARK JISU (KR)
JUNG HYEJUNG (KR)
Application Number:
PCT/KR2018/011045
Publication Date:
March 28, 2019
Filing Date:
September 19, 2018
Export Citation:
Assignee:
SKIN QC CO LTD (KR)
International Classes:
A61K8/44; A23L33/10; A61K31/198; A61Q19/02
Foreign References:
| US20110045036A1 | 2011-02-24 | |||
| KR20160072239A | 2016-06-22 |
Other References:
SLOMINSKI, A. ET AL.: "Positive Regulation of Melanin Pigmentation by Two Key Substrates of the Melanogenic Pathway, L-tyrosine and L-dopa", JOURNAL OF CELL SCIENCE, vol. 89, 1988, pages 287 - 296, XP055585136
MENTEL, M. ET AL.: "Innovative Peptide Technologies for Even, Young and Healthy Looking Skin", SOFW JOURNAL, vol. 138, 2012, pages 22 - 33, XP055585138
PICKART, L. ET AL.: "GHK Peptide as a Natural Modulator of Multiple Cellular Pathways in Skin Regeneration", BIOMED RESEARCH INTERNATIONAL, vol. 2015, 2015, pages 1 - 7, XP055471716, DOI: doi:10.1155/2015/648108
PARK, J. ET AL.: "D-tyrosine Negatively Regulates Melanin Synthesis by Competitively Inhibiting Tyrosinase Activity", PIGMENT CELL & MELANOMA RESEARCH, vol. 31, 9 November 2017 (2017-11-09), pages 374 - 383, XP055585143
MENTEL, M. ET AL.: "Innovative Peptide Technologies for Even, Young and Healthy Looking Skin", SOFW JOURNAL, vol. 138, 2012, pages 22 - 33, XP055585138
PICKART, L. ET AL.: "GHK Peptide as a Natural Modulator of Multiple Cellular Pathways in Skin Regeneration", BIOMED RESEARCH INTERNATIONAL, vol. 2015, 2015, pages 1 - 7, XP055471716, DOI: doi:10.1155/2015/648108
PARK, J. ET AL.: "D-tyrosine Negatively Regulates Melanin Synthesis by Competitively Inhibiting Tyrosinase Activity", PIGMENT CELL & MELANOMA RESEARCH, vol. 31, 9 November 2017 (2017-11-09), pages 374 - 383, XP055585143
Attorney, Agent or Firm:
SON, Min (KR)
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