Title:
SKIN WHITENING COMPOSITION CONTAINING CHEMOKINE
Document Type and Number:
WIPO Patent Application WO/2016/018001
Kind Code:
A1
Abstract:
The present invention relates to a composition containing a chemokine, especially, an interferon-inducible T-cell alpha chemoattractant (ITAC) so as to decrease the gene expression of a factor related to melanin pigment formation in a melanin-forming cell, thereby exhibiting a skin whitening effect.
Inventors:
LEE EUN KYUNG (KR)
HAN JI YEON (KR)
CHO EUN GYUNG (KR)
LEE TAE RYONG (KR)
CHOI HYUN JUNG (KR)
HAN JI YEON (KR)
CHO EUN GYUNG (KR)
LEE TAE RYONG (KR)
CHOI HYUN JUNG (KR)
Application Number:
PCT/KR2015/007721
Publication Date:
February 04, 2016
Filing Date:
July 24, 2015
Export Citation:
Assignee:
AMOREPACIFIC CORP (KR)
International Classes:
A61K8/64; A61K38/19; A61P17/00; A61Q19/02
Domestic Patent References:
| WO2002059301A1 | 2002-08-01 | |||
| WO2004005892A2 | 2004-01-15 |
Foreign References:
| KR20130056955A | 2013-05-31 |
Other References:
COLE, K. E. ET AL.: "Interferon-inducible T cell alpha clemoatractant (I-TAC): a novel non-ELR CXC chemokine with patent activity on activated T cells through selective high affinity binding to CXCR3", J. EXP. MED., vol. 187, no. 12, 15 June 1998 (1998-06-15), pages 2009 - 2021, XP002085475
MOHAN, K. ET AL.: "IFN-gamma-inducible T cell alpha chemoattractant is a potent stimulator of normal human blood T lymphocyte transendothelial migration: differential regulation by IFN-gamma and TNF-alpha", J. IMMUNOL., vol. 168, no. 12, 15 June 2002 (2002-06-15), pages 6420 - 6428, XP055391254
WANG, CLAIRE Q. F. ET AL.: "IL -17 and TNF synergistically modulate cytokine expression while suppressing melanogenesis: potential relevance to psoriasis", J. INVEST DERMATOL., vol. 133, no. 12, 2013, pages 2741 - 2752, XP055391259
See also references of EP 3162358A4
MOHAN, K. ET AL.: "IFN-gamma-inducible T cell alpha chemoattractant is a potent stimulator of normal human blood T lymphocyte transendothelial migration: differential regulation by IFN-gamma and TNF-alpha", J. IMMUNOL., vol. 168, no. 12, 15 June 2002 (2002-06-15), pages 6420 - 6428, XP055391254
WANG, CLAIRE Q. F. ET AL.: "IL -17 and TNF synergistically modulate cytokine expression while suppressing melanogenesis: potential relevance to psoriasis", J. INVEST DERMATOL., vol. 133, no. 12, 2013, pages 2741 - 2752, XP055391259
See also references of EP 3162358A4
Attorney, Agent or Firm:
YOON, Dong Yol (KR)
윤동열 (KR)
윤동열 (KR)
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