Title:
SKIN WHITENING COMPOSITION CONTAINING MANNOSYLERYTHRITOL LIPID
Document Type and Number:
WIPO Patent Application WO/2018/048127
Kind Code:
A1
Abstract:
The present invention relates to a skin whitening composition containing mannosylerythritol lipid (MEL) as an active ingredient. The skin whitening composition according to the present invention suppresses the formation of skin melanocytes and improves the overall skin tone, and thus gives effectiveness of exhibiting clean, darkness-relieved, and bright skin. In addition, the composition can be easily formulated, and thus can be utilized in a high content for various dosage forms even without using a particular additional ingredient for formulating effective ingredient.
Inventors:
YOO JAE WON (KR)
HWANG YOON KYUN (KR)
BIN SUNG-AH (KR)
KIM YONG JIN (KR)
LEE JOHN HWAN (KR)
HWANG YOON KYUN (KR)
BIN SUNG-AH (KR)
KIM YONG JIN (KR)
LEE JOHN HWAN (KR)
Application Number:
PCT/KR2017/009369
Publication Date:
March 15, 2018
Filing Date:
August 28, 2017
Export Citation:
Assignee:
AMOREPACIFIC CORP (KR)
International Classes:
A61K8/60; A61K8/02; A61Q19/02
Domestic Patent References:
| WO2007060956A1 | 2007-05-31 |
Foreign References:
| KR20160000747A | 2016-01-05 |
Other References:
ZHAO, XIAOXIAN ET AL.: "Mannosylerythritol Lipid Is a Potent Inducer of Apoptosis and Differentiation of Mouse Melanoma Cells in Culture", CANCER RESEARCH, vol. 59, no. 2, 15 January 1999 (1999-01-15), pages 482 - 486, XP055139167
FAN, LINLIN ET AL.: "Characterization and Inducing Melanoma Cell Apoptosis Activity of Mannosylerythritol Lipids-A Produced from Pseudozyma Aphidis", PLOS ONE, vol. 11, no. 2, 1 February 2016 (2016-02-01), pages 1 - 17, XP055497462, DOI: doi:10.1371/journal.pone.0148198
TAKAHASHI, MAKOTO ET AL.: "Glycolipid Biosurfactants, Mannosylerythritol Lipids, Show Antioxidant and Protective Effects against H202-induced Oxidative Stress in Cultured Human Skin Fibroblasts", JOURNAL OF OLEO SCIENCE, vol. 61, no. 8, 2012, pages 457 - 464, XP055497467, DOI: doi:10.5650/jos.61.457
FAN, LINLIN ET AL.: "Characterization and Inducing Melanoma Cell Apoptosis Activity of Mannosylerythritol Lipids-A Produced from Pseudozyma Aphidis", PLOS ONE, vol. 11, no. 2, 1 February 2016 (2016-02-01), pages 1 - 17, XP055497462, DOI: doi:10.1371/journal.pone.0148198
TAKAHASHI, MAKOTO ET AL.: "Glycolipid Biosurfactants, Mannosylerythritol Lipids, Show Antioxidant and Protective Effects against H202-induced Oxidative Stress in Cultured Human Skin Fibroblasts", JOURNAL OF OLEO SCIENCE, vol. 61, no. 8, 2012, pages 457 - 464, XP055497467, DOI: doi:10.5650/jos.61.457
Attorney, Agent or Firm:
KIM, Sung Ho et al. (KR)
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