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Title:
SLEEP IMPROVING AGENT
Document Type and Number:
WIPO Patent Application WO/2017/204321
Kind Code:
A1
Abstract:
The present invention provides a heat shock protein expression inducing agent, more specifically, a heat shock protein expression inducing agent containing a compound represented by formula (I) or a salt thereof. (In the formula, R represents a lower alkyl, phenyl, or hydroxyphenyl.)

Inventors:
GOTO KAZUNORI (JP)
NAKAHIGASHI JUN (JP)
SATO ATSUYA (JP)
HIRAYAMA YOSUKE (JP)
HORIKOSHI MOERI (JP)
KOUDA NORIYUKI (JP)
INOUE SYOICHIRO (JP)
SATO IKUTARO (JP)
KATO MANAMI (JP)
Application Number:
PCT/JP2017/019644
Publication Date:
November 30, 2017
Filing Date:
May 26, 2017
Export Citation:
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Assignee:
AMINO UP CHEMICAL CO LTD (JP)
OTSUKA PHARMA CO LTD (JP)
International Classes:
A61K31/4985; A61P25/00; A61P25/18; A61P25/20; A61P43/00
Domestic Patent References:
WO2012043808A12012-04-05
WO2015013397A22015-01-29
WO2013047055A12013-04-04
WO2012043808A12012-04-05
Foreign References:
JP2003525850A2003-09-02
JP2007504235A2007-03-01
JP2016105477A2016-06-09
JP2003252896A2003-09-10
Other References:
CORNACCHIA, C. ET AL.: "2,5-diketopiperazines as neuroprotective agents", MINI-REVIEWS IN MEDICINAL CHEMISTRY, vol. 12, 2012, pages 2 - 12, XP055457346, ISSN: 1389-5575
ITO, TOMOHIRO ET AL.: "Enzyme-treated asparagus extract promotes expression of heat shock protein and exerts antistress effects", JOURNAL OF FOOD SCIENCE, vol. 79, no. 3, 2014, pages H413 - H419, XP055553610, ISSN: 1750-3841
DOKLADY BIOLOGICAL SCIENCES, vol. 449, 2013, pages 89 - 92
DOKLADY BIOLOGICAL SCIENCES, vol. 461, 2015, pages 76 - 79
EXP. THER. MED., vol. 4, no. 4, October 2012 (2012-10-01), pages 627 - 632
J. BIOL. CHEM., vol. 275, no. 27, 2000, pages 20822 - 20828
J. PEPTIDE SCI., vol. 10, 2004, pages 737 - 737
WADA T. ET AL., BRAIN RES BULL., vol. 69, 2006, pages 388 - 92
MIYAZAKI K. ET AL., PLOS ONE., vol. 8, 2013, pages e55452
SEI H. ET AL., LIFE SCI., vol. 73, 2003, pages 53 - 59
Attorney, Agent or Firm:
SAMEJIMA, Mutsumi et al. (JP)
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