SLOW-RELEASE CILOSTAZOL TABLET HAVING AN IMPROVED ELUTION RATE AND MINIMAL SIDE EFFECTS

WIPO Patent Application WO/2011/037281

A1

The present invention relates to a slow-release tablet of cilostazol which is a pharmacologically active component efficacious in the suppression of blood platelet aggregation and the promotion of vascular relaxation by inhibiting phosphodiesterase types; and, more specifically, provided is a slow-release cilostazol tablet of which the elution time is extended such that it can be taken once a day for expediency of drug-taking, and which minimises the occurrence of headache which is a side effect during the taking of cilostazol preparations of the prior art and therefore improves the convenience of drug-taking for women, the elderly and children. Also provided is a slow-release cilostazol tablet which exhibits a stable elution pattern without any variation in the percentage eluted depending on the pH in the stomach in addition to an effect whereby release of the drug is delayed, by using a release-controlling polymer consisting of a mixture of hydroxypropyl methyl cellulose and a carbomer.

CHOI YOUN-WOONG (KR)
MIN BYUNG-GU (KR)
CHO SANG-MIN (KR)

PCT/KR2009/005420

March 31, 2011

September 23, 2009

Click for automatic bibliography generation  

KOREA UNITED PHARM INC (KR)
CHOI YOUN-WOONG (KR)
MIN BYUNG-GU (KR)
CHO SANG-MIN (KR)

A61K9/22; A61K31/41; A61K47/38; A61P7/02; A61P9/10

WO2000057881A1

2000-10-05

KR20070024254A	2007-03-02
KR20070021830A	2007-02-23
KR20080074178A	2008-08-12
KR20040084930A	2004-10-06
US20020058066A1	2002-05-16

See also references of EP 2481398A4
AM J CARDIOL, vol. 87, 2001, pages 28D - 33D

KIM, HONG-GYUN (KR)
김홍균 (KR)

View/Download PDF      PDF Help

Previous Patent: DEVICE FOR DISPLAYING FLOOR INFORMATION OF OPERATING ELEVATOR USING ACCELERATION SENSOR

Next Patent: SLIDE SWITCH FOR HAIR IRON