Title:
SMAC PEPTIDOMIMETICS AND THE USES THEREOF
Document Type and Number:
WIPO Patent Application WO2005069888
Kind Code:
A3
Abstract:
The invention relates to peptidomimetics of Smac which function as inhibitors of Inhibitor of Apoptosis Proteins. The invention also relates to the use of these peptidomimetics for inducing apoptotic cell death and for sensitizing cells to inducers of apoptosis.
Inventors:
WANG SHAOMENG (US)
SUM HAIYING (US)
NIKOLOVSKA-COLESKA ZANETA (US)
YANG CHAO-YIO (US)
XU LIANG (US)
SUM HAIYING (US)
NIKOLOVSKA-COLESKA ZANETA (US)
YANG CHAO-YIO (US)
XU LIANG (US)
Application Number:
PCT/US2005/001363
Publication Date:
December 29, 2005
Filing Date:
January 18, 2005
Export Citation:
Assignee:
UNIV MICHIGAN (US)
WANG SHAOMENG (US)
SUM HAIYING (US)
NIKOLOVSKA-COLESKA ZANETA (US)
YANG CHAO-YIO (US)
XU LIANG (US)
WANG SHAOMENG (US)
SUM HAIYING (US)
NIKOLOVSKA-COLESKA ZANETA (US)
YANG CHAO-YIO (US)
XU LIANG (US)
International Classes:
A61K38/05; A61K38/06; C07K5/062; C07K5/083; C12N5/07; C12N5/09; (IPC1-7): A61K38/05; A61K38/06; C07K5/062; C07K5/083
Domestic Patent References:
| WO2004005248A1 | 2004-01-15 |
Foreign References:
| US6608026B1 | 2003-08-19 | |||
| US20020177557A1 | 2002-11-28 |
Other References:
See also references of EP 1715882A4
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