Title:
SMALL MOLECULE INHIBITOR OF THE NUCLEAR TRANSLOCATION OF ANDROGEN RECEPTOR FOR THE TREATMENT OF CASTRATION-RESISTANT PROSTATE CANCER
Document Type and Number:
WIPO Patent Application WO/2017/165822
Kind Code:
A8
Abstract:
A compound, or a stereoisomer, pharmaceutically acceptable salt, or ester thereof, according to formula (III) or according to Table A, a pharmaceutical composition comprising said compound and at least one pharmaceutically acceptable additive, and a method for treating prostate cancer in a subject, comprising administering to the subject a therapeutically effective amount of said compound.
Inventors:
WIPF PETER (US)
JOHNSON JAMES K (US)
SKODA ERIN M (US)
NELSON JOEL B (US)
WANG ZHOU (US)
TAI SERENE (US)
TAKUBO KEITA (US)
MILLIGAN JOHN (US)
JOHNSON JAMES K (US)
SKODA ERIN M (US)
NELSON JOEL B (US)
WANG ZHOU (US)
TAI SERENE (US)
TAKUBO KEITA (US)
MILLIGAN JOHN (US)
Application Number:
PCT/US2017/024105
Publication Date:
November 02, 2017
Filing Date:
March 24, 2017
Export Citation:
Assignee:
UNIV OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US)
International Classes:
C07D295/185; A61K31/12; A61K31/407; A61K31/42; A61K31/435; A61K31/445; A61K31/46; A61K31/47; A61K31/495; A61K31/496; A61K31/498; A61P35/00; C07C49/563; C07D217/16; C07D401/08; C07D403/04; C07D403/06; C07D405/06; C07D407/04; C07D409/08; C07D413/12; C07D451/02; C07D487/04
Attorney, Agent or Firm:
GARDNER, Gillian (US)
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