Title:
SMALL-MOLECULE SULFUR-CONTAINING HETEROCYCLIC COMPOUND
Document Type and Number:
WIPO Patent Application WO/2021/115495
Kind Code:
A1
Abstract:
The present invention relates to a sulfur-containing heterocyclic compound, characterized by: a compound represented by the following structural formula (I) or stereoisomer thereof, a geometric isomer, a tautomer, a racemate, a deuterated isotope derivative, a hydrate, a solvate, a metabolite, and a pharmaceutically acceptable salt or prodrug; the compound can be used as a ROCK kinase inhibitor, and a composition containing such inhibitor, particularly a drug, and the use of such inhibitors in the treatment and prevention of disease. Specifically, the compounds can be used for treating ocular diseases (such as glaucoma and retinal diseases).
Inventors:
SHEN WANG (CN)
DANG KUIFENG (CN)
ZHANG CHAO (CN)
CHEN CHUNMING (CN)
SHAN LIHONG (CN)
DING WEN (CN)
WANG XIN (CN)
MI JIACHEN (CN)
SUN YABO (CN)
SHENG XIAXIN (CN)
SHEN JIALEI (CN)
LI YONG (CN)
DANG KUIFENG (CN)
ZHANG CHAO (CN)
CHEN CHUNMING (CN)
SHAN LIHONG (CN)
DING WEN (CN)
WANG XIN (CN)
MI JIACHEN (CN)
SUN YABO (CN)
SHENG XIAXIN (CN)
SHEN JIALEI (CN)
LI YONG (CN)
Application Number:
PCT/CN2021/073564
Publication Date:
June 17, 2021
Filing Date:
January 25, 2021
Export Citation:
Assignee:
VIVAVISION BIOTECH INC (CN)
International Classes:
C07D275/04; A61P27/02; A61P27/06; C07D495/04
Domestic Patent References:
| WO2019178324A1 | 2019-09-19 |
Foreign References:
| CN111217834A | 2020-06-02 | |||
| CN110248939A | 2019-09-17 | |||
| CN110382481A | 2019-10-25 |
Attorney, Agent or Firm:
J.Z.M.C. PATENT AND TRADEMARK LAW OFFICE (GENERAL PARTNERSHIP) (CN)
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