SMALL RNA AND USE THEREOF IN TREATMENT OF HYPERLIPIDEMIA

Title:

SMALL RNA AND USE THEREOF IN TREATMENT OF HYPERLIPIDEMIA

Document Type and Number:

WIPO Patent Application WO/2023/143479

Kind Code:

A1

Abstract:

Provided are small RNA and a use thereof in the treatment of hyperlipidemia. Specifically, provided are an isolated nucleic acid molecule as shown in any one of SEQ ID NO: 1 to SEQ ID NO: 75, a vector comprising same, a host cell, a pharmaceutical composition, and a use of the nucleic acid molecule in the preparation of a drug for treating hyperlipidemia.

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Inventors:

JIANG CHENGYU (CN)
TANG KEGONG (CN)
CHEN MINGRUI (CN)

Application Number:

PCT/CN2023/073495

Publication Date:

August 03, 2023

Filing Date:

January 27, 2023

Export Citation:

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Assignee:

INST BASIC MEDICAL SCIENCES CAMS (CN)

International Classes:

C12N15/113; A61K31/7088; A61P3/06

Foreign References:

CN101501193A	2009-08-05
CN109985243A	2019-07-09
CN113116918A	2021-07-16
CN105829535A	2016-08-03
CN106267207A	2017-01-04
CN111818940A	2020-10-23

Other References:

XU, HAINAN ET AL.: "Small Interfering RNA Inclisiran", ADVANCES IN CARDIOVASCULAR DISEASES, vol. 42, no. 7, 25 July 2021 (2021-07-25), XP009547657, ISSN: 1004-3934

Attorney, Agent or Firm:

GE CHENG & CO., LTD. (CN)

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