Title:
SMOOTHENED MODULATORS AND METHODS OF USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2014/043608
Kind Code:
A3
Abstract:
Compounds of general Formulas (I), (IA), (IB) are described, along with compositions containing the same and methods of use thereof, inhibiting the hedgehog pathway in a cell or inhibiting unwanted proliferation of a cell.
Inventors:
CHEN WEI (US)
WANG JIANGBO (US)
MOOK ROBERT A JR (US)
BARAK LAWRENCE S (US)
LYERLY H KIM (US)
RIBEIRO ANTHONY ANGELO (US)
WANG JIANGBO (US)
MOOK ROBERT A JR (US)
BARAK LAWRENCE S (US)
LYERLY H KIM (US)
RIBEIRO ANTHONY ANGELO (US)
Application Number:
PCT/US2013/059905
Publication Date:
July 16, 2015
Filing Date:
September 16, 2013
Export Citation:
Assignee:
UNIV DUKE (US)
International Classes:
A61K31/445
Domestic Patent References:
| WO2009154739A2 | 2009-12-23 | |||
| WO2006028958A2 | 2006-03-16 |
Foreign References:
| US20080269215A1 | 2008-10-30 | |||
| US20110046143A1 | 2011-02-24 |
Other References:
DATABASE PUBCHEM [online] 30 May 2013 (2013-05-30), XP055265503, Database accession no. 71458712
Attorney, Agent or Firm:
MYERS BIGEL SIBLEY & SAJOVEC, P.A. (Raleigh, North Carolina, US)
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