SNAKE VENOM FOR USE IN THE TREATMENT PRIOR TO A SURGICAL PROCEDURE IN THE BRAIN

Title:

SNAKE VENOM FOR USE IN THE TREATMENT PRIOR TO A SURGICAL PROCEDURE IN THE BRAIN

Document Type and Number:

WIPO Patent Application WO/2015/184380

Kind Code:

A8

Abstract:

A treatment for reducing brain or other injury that can be used before, during, or after a surgical treatment or other injury to the brain to decrease or prevent subsequent damage. Injury to the brain during surgery or from other trauma can create elevations in brain edema and blood-brain barrier disruption thereby decreasing neurological recovery and patient outcomes. Treatment of the brain with venom, including snake venom, prior to or after injury can reduce the bleeding, swelling, and/or inflammation that results from the trauma. These pre-conditioning and/or rapid-conditioning treatments of the brain with venom can reduce brain edema and blood-brain barrier disruption and improve patient outcomes.

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Inventors:

ZHANG JOHN H (US)
KIM CHERINE (US)
SHERCHAN PRATIVA (US)
KRAFFT PAUL (US)
MCBRIDE DEVIN (US)
LEKIC TIM (US)

Application Number:

PCT/US2015/033365

Publication Date:

January 26, 2017

Filing Date:

May 29, 2015

Export Citation:

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Assignee:

UNIV LOMA LINDA (US)
LOMA LINDA UNIV MEDICAL CENTER (US)

International Classes:

A61K35/583; A61P41/00

Attorney, Agent or Firm:

ALTMAN, Daniel, E. (US)

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