Title:
SODIUM CHANNEL BLOCKING COMPOUNDS, DERIVATIVES THEREOF, AND METHODS OF THEIR USE
Document Type and Number:
WIPO Patent Application WO/2024/054622
Kind Code:
A3
Abstract:
The invention provides compounds that are useful for treatment of conditions associated with aberrant activity of voltage gated sodium channel Navl.8, and methods of treating a subject with those compounds for conditions such as pain, itch, and cough.
Inventors:
BAJJI ASHOK (US)
KAUFMAN MICHAEL (US)
BALKOVEC JAMES (US)
KAUFMAN MICHAEL (US)
BALKOVEC JAMES (US)
Application Number:
PCT/US2023/032280
Publication Date:
April 18, 2024
Filing Date:
September 08, 2023
Export Citation:
Assignee:
LATIGO BIOTHERAPEUTICS INC (US)
International Classes:
A61K31/395; A61K31/166; A61K31/167; A61K31/44; A61K31/4995; A61K31/33
Domestic Patent References:
| WO2009049183A1 | 2009-04-16 | |||
| WO2022094244A1 | 2022-05-05 | |||
| WO2023154519A1 | 2023-08-17 |
Foreign References:
| US10647661B2 | 2020-05-12 | |||
| US20120202817A1 | 2012-08-09 |
Other References:
DATABASE PUBCHEM COMPOUND 16 March 2019 (2019-03-16), ANONYMOUS: "N-(3-carbamoylphenyl)-3-[2methoxy-4-(trifluoromethoxy)phenoxy]-5-(trifluoromethyl)pyridine-2carboxamide", XP093163413, Database accession no. 137406440
Attorney, Agent or Firm:
SCHOEN, Adam, M. et al. (US)
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