SOLID FORM OF AZETIDINE DERIVATIVE AND PREPARATION METHOD THEREFOR AND USE THEREOF - SICHUAN KELUN BIOTECH BIOPHARMACEUTICAL CO LTD

Title:

SOLID FORM OF AZETIDINE DERIVATIVE AND PREPARATION METHOD THEREFOR AND USE THEREOF

Document Type and Number:

WIPO Patent Application WO/2018/223859

Kind Code:

A1

Abstract:

The present invention relates to a solid form of a compound of formula (I), a method for preparing the solid form, a pharmaceutical composition comprising the solid form, and the use of the solid form in the treatment of Janus kinase (JAK)-associated diseases, including, for example, inflammatory diseases, autoimmune diseases and cancers.

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Inventors:

GE JIANHUA (CN)
HAN ZENGYING (CN)
CHEN FENGCHUN (CN)
JIAO SHIHU (CN)
ZHANG HONG (CN)
ZHANG PING (CN)
WANG LICHUN (CN)
WANG JINGYI (CN)

Application Number:

PCT/CN2018/088645

Publication Date:

December 13, 2018

Filing Date:

May 28, 2018

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Assignee:

SICHUAN KELUN BIOTECH BIOPHARMACEUTICAL CO LTD (CN)

International Classes:

C07D487/04; A61K31/519; A61P19/02; A61P29/00; A61P35/00; A61P37/00

Domestic Patent References:

WO2017097224A1	2017-06-15
WO2017082759A1	2017-05-18
WO2010039939A1	2010-04-08

Foreign References:

CN102026999A

2011-04-20

Other References:

"Remington's Pharmaceutical Sciences", 1990
See also references of EP 3636647A4

Attorney, Agent or Firm:

NTD UNIVATION INTELLECTUAL PROPERTY AGENCY LTD (CN)

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