Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
SOLID FORMS OF A THIOPHOSPHORAMIDATE NUCLEOTIDE PRODRUG
Document Type and Number:
WIPO Patent Application WO/2013/142124
Kind Code:
A8
Abstract:
The present application relates to solid state forms, for example, crystalline forms of 2'-C-methyluridine-5'-(O-phenyl-N-(S)-1-(isopropoxycarbonyl)ethyl)thiophosphoramidate, pharmaceutical compositions that can include one or more solid forms of 2'-C-methyluridine-5'-(O-phenyl-N-(S)-1-(isopropoxycarbonyl)ethyl)thiophosphoramidate, and methods of treating or ameliorating diseases and/or conditions with one or more solid forms of 2'-C-methyluridine-5'-(O-phenyl-N-(S)-1-(isopropoxy carbonyl)ethyl)thiophosphoramidate. Also disclosed herein are methods of treating diseases and/or conditions with one or more solid forms of 2'-C-methyluridine-5'-(O-phenyl-N-(S)-1-(isopropoxycarbonyl)ethyl)thiophosphoramidate in combination with one or more other agents.

Inventors:
KULDIPKUMAR, Anuj, K. (282 Fellsway West, Medford, MA, 02155, US)
MEDEK, Ales (14 Lockland Road, Winchester, MA, 01890, US)
FERRIS, Lori, Ann (60 Cushing Street, Medford, MA, 02155, US)
MUDUNURI, Praveen (7 Charlesbank Way, Apt. A.Waltham, MA, 02453, US)
JUNG, Young, Chun (22 Webb Street, Lexington, MA, 02420, US)
WILLCOX, David, Richard (73 Elmwood Road, Wellesley, MA, 02481, US)
WALDO, Michael (4 Patricia Drive, Grafton, MA, 01519, US)
NUGENT, William, Aloysius (P.O. Box 1021, Manomet, MA, 02345, US)
Application Number:
US2013/030267
Publication Date:
May 15, 2014
Filing Date:
March 11, 2013
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
VERTEX PHARMACEUTICALS INCORPORATED (50 Northern Avenue, Boston, MA, 02210, US)
International Classes:
C07H19/06; A61K31/7072; A61P31/14
Attorney, Agent or Firm:
O'BRIEN, Jonathan P., et al. (Honigman Miller Schwartz and Cohn LLP, 350 East Michigan Avenue Suite 30, Kalamazoo MI, 49007-3800, US)
Download PDF: