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Title:
SOLID PHASE CARRIER, LIGAND-BOUND SOLID PHASE CARRIER, METHOD FOR DETECTING OR SEPARATING TARGET SUBSTANCE, AND METHOD FOR PRODUCING SOLID PHASE CARRIER
Document Type and Number:
WIPO Patent Application WO/2016/039293
Kind Code:
A1
Abstract:
Provided is a solid phase carrier which exhibits high water dispersibility, in which ligands readily bond to a reactive functional group, in which non-specific adsorption is suppressed, and by which detection or the like of a target substance can be carried out with high sensitivity and low noise when a ligand is bound thereto. The solid phase carrier is obtained by binding a polymer, which contains a structural unit represented by formula (1) and a structural unit represented by formula (2). (In formula (1), R1 denotes a hydrogen atom or a methyl group, and R2 denotes an organic group having a zwitterion structure) (In formula (2), R3 denotes a hydrogen atom or a methyl group, R4 denotes -(C=O)-O-* or -(C=O)-NR6-*(therein, R6 denotes a hydrogen atom or a methyl group and * denotes the site that bonds to R5 in formula (2)) or a phenylene group, R5 denotes a hydrogen atom or an organic group having a reactive functional group in cases where R4 is -(C=O)-O-*, and R5 denotes an organic group having a reactive functional group in cases where R4 is -(C=O)-NR6-* or a phenylene group, with the proviso that R5 is not an organic group having a zwitterion structure.)

Inventors:
UEYA YUUICHI (JP)
Application Number:
PCT/JP2015/075333
Publication Date:
March 17, 2016
Filing Date:
September 07, 2015
Export Citation:
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Assignee:
JSR CORP (JP)
JSR LIFE SCIENCES CORP (JP)
International Classes:
G01N33/543; C08F257/02; C08F293/00; G01N33/545; G01N33/547
Domestic Patent References:
WO2013047527A12013-04-04
Foreign References:
JP2009542862A2009-12-03
Other References:
HIROMI KITANO ET AL.: "Correlation between Biocompatibility of Polymer Materials and Their Hydration Structure", KOBUNSHI, vol. 58, no. 2, February 2009 (2009-02-01), pages 74 - 77, XP008185540
See also references of EP 3193172A4
Attorney, Agent or Firm:
THE PATENT CORPORATE BODY ARUGA PATENT OFFICE (JP)
Patent business corporation Alga patent firm (JP)
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