Title:
SOLID PREPARATION
Document Type and Number:
WIPO Patent Application WO/1992/001453
Kind Code:
A1
Abstract:
A solid preparation prepared from a powder obtained by dissolving 3-[3-(6-benzoyloxy-3-cyano-2-pyridyloxycarbonyl)benzoyl]-1-ethoxymethyl-5-fluorouracil (BOF-A2) and a water-soluble high-molecular compound completely in an organic solvent and removing the solvent to leave an amorphous substance behind. The preparation serves to promote the absorption of BOF-A2 through the digestive tract by increasing its solubility.
Inventors:
NISHIBAYASHI TORU (JP)
ISHIZUE YOSHIHIRO (JP)
ISHIDA KOZO (JP)
KUBO MASANORI (JP)
ISHIZUE YOSHIHIRO (JP)
ISHIDA KOZO (JP)
KUBO MASANORI (JP)
Application Number:
PCT/JP1991/000951
Publication Date:
February 06, 1992
Filing Date:
July 17, 1991
Export Citation:
Assignee:
OTSUKA PHARMA CO LTD (JP)
International Classes:
A61K9/14; A61K9/16; A61K31/505; A61K47/38; (IPC1-7): A61K9/14; A61K9/16; A61K31/505; A61K47/38
Foreign References:
JPS63201127A | 1988-08-19 | |||
JPH0249720A | 1990-02-20 | |||
JPS5899411A | 1983-06-13 | |||
JPS63115817A | 1988-05-20 | |||
JPS58109411A | 1983-06-29 |
Other References:
See also references of EP 0489181A4
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