SOLID PREPARATION - LINTEC CORP

Title:

SOLID PREPARATION

Document Type and Number:

WIPO Patent Application WO/2011/118453

Kind Code:

A1

Abstract:

Provided are a solid preparation that can easily regulate the dissolvability of medication, and a method to improve the dissolvability of medication. The disclosed solid preparation (1) is provided with a medication-containing part (2) that contains medication, a gel-forming layer (4) that coats the medication-containing part (2) and forms a gel by absorbing water, and, if necessary, an intermediate layer (3) interposed between the medication-containing part (2) and the gel-forming layer (4). By including a foaming agent (such as sodium bicarbonate) in the medication-containing part (2) and/or the intermediate layer (3), the dissolvability of the medication is improved. The medication-containing part (2) can contain cationic or basic medication, and the gel-forming layer (4) can contain an anionic or acidic polymer. The gel-forming layer (4) can be coated by a surface layer (adhesion prevention layer) (5).

Inventors:

TAKANO YOUICHI (JP)

Application Number:

PCT/JP2011/056055

Publication Date:

September 29, 2011

Filing Date:

March 15, 2011

Export Citation:

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Assignee:

LINTEC CORP (JP)
ASKA PHARM CO LTD (JP)
TAKANO YOUICHI (JP)

International Classes:

A61K9/46; A61K9/28; A61K9/70; A61K47/02; A61K47/04; A61K47/30; A61K47/38

Domestic Patent References:

WO2005097080A1	2005-10-20
WO2002087622A1	2002-11-07
WO2005097080A1	2005-10-20

Foreign References:

JP2005519865A	2005-07-07
JPH09221416A	1997-08-26
JP2002543109A	2002-12-17
JPS62207208A	1987-09-11
JPS63264518A	1988-11-01
JPH07277959A	1995-10-24
JP4372347B2	2009-11-25
JP2008037794A	2008-02-21

Other References: