SOLID-STATE BETA DETECTOR FOR MICROFLUIDIC DEVICES

WIPO Patent Application WO2004095061

A3

A beta detector assembly for use in the synthesis and analysis of radiopharmaceuticals, such as in microfluidic radiochromatography. The beta detector assembly includes a base, preferably fabricated from glass so as to take advantage of electroosmotic flow, that serves as the body of the beta detector assembly. A microfluidic channel passes through the length of the base. A solid-state charge particle detector, for detecting beta particles, is provided and is positioned with respect to the base so as to receive beta particles. A portion of the base is disposed between the microfluidic channel and the solid-state charge particle detector and has a thickness that is selected to substantially allow transmission of beta particles there thru for detection by the charge particle detector. In one embodiment, the base is fabricated of glass. In another embodiment, the base is fabricated of silicon such that the base and the solid-state charge particle detector are integral.

ALVORD WILLIAM C (US)
BUCHANAN CHARLES R (US)
MATTEO JOSEPH C (US)
PADGETT HENRY C (US)
COLLIER THOMAS L (US)

PCT/US2004/012499

June 23, 2005

April 21, 2004

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MOLECULAR TECHNOLOGIES INC (US)
ALVORD WILLIAM C (US)
BUCHANAN CHARLES R (US)
MATTEO JOSEPH C (US)
PADGETT HENRY C (US)
COLLIER THOMAS L (US)

A61K51/00; B01D57/02; B01D59/42; B01D59/50; B01L3/00; C02F1/40; C02F11/00; C25B11/00; C25B13/00; G01J1/42; G01N25/20; G01N27/26; G01N27/27; G21G4/08; G21H5/02; H01L27/00; A61B; G01T; (IPC1-7): B01D57/02; B01D59/42; B01D59/50; C02F1/40; C02F11/00; C25B11/00; C25B13/00; G01J1/42; G01N25/20; H01L27/00

US6379929B1	2002-04-30
US6214191B1	2001-04-10
JPS62239047A	1987-10-19
US5591644A	1997-01-07

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