Title:
SOMATOSTATIN-DOPAMINE CHIMERIC ANALOGS
Document Type and Number:
WIPO Patent Application WO/2014/070971
Kind Code:
A3
Abstract:
The present invention relates to novel somatostatin-dopamine chimeric analogs and their therapeutic uses for the inhibition, prevention, and/or treatment of neoplasia, neuroendocrine tumors, Cushing's disease/syndrome, and other conditions.
Inventors:
DONG ZHENG XIN (US)
SHEN YEELANA (US)
KIM SUN HYUK (US)
SHEN YEELANA (US)
KIM SUN HYUK (US)
Application Number:
PCT/US2013/067661
Publication Date:
July 03, 2014
Filing Date:
October 31, 2013
Export Citation:
Assignee:
IPSEN PHARMA SAS (FR)
DONG ZHENG XIN (US)
SHEN YEELANA (US)
KIM SUN HYUK (US)
DONG ZHENG XIN (US)
SHEN YEELANA (US)
KIM SUN HYUK (US)
International Classes:
A61K38/08; A61K38/31; A61K38/12; C07D457/00; C07D519/02
Foreign References:
| US20060063704A1 | 2006-03-23 | |||
| US6465613B1 | 2002-10-15 | |||
| US20050118099A1 | 2005-06-02 | |||
| US20110064742A1 | 2011-03-17 | |||
| US20050222025A1 | 2005-10-06 | |||
| US20070154392A1 | 2007-07-05 | |||
| US20060052389A1 | 2006-03-09 |
Other References:
ROSS ET AL.: "Synthetic mimetics of protein secondary structure domains", PHIL. TRANS. R. SOC. A, vol. 368, 2010, pages 989 - 1008, XP055253192
ROHRER ET AL.: "Rapid Identification of Subtype-Selective Agonists of the Somatostatin Receptor Through Combinatorial Chemistry", SCIENCE, vol. 282, 23 October 1998 (1998-10-23), pages 737 - 740, XP002189092
ROHRER ET AL.: "Rapid Identification of Subtype-Selective Agonists of the Somatostatin Receptor Through Combinatorial Chemistry", SCIENCE, vol. 282, 23 October 1998 (1998-10-23), pages 737 - 740, XP002189092
Attorney, Agent or Firm:
UHM, Tony, K. et al. (Incorporated27 Maple Stree, Milford MA, US)
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