SPATIALLY DIRECTED INTERACTION ON A SOLID SURFACE

Title:

SPATIALLY DIRECTED INTERACTION ON A SOLID SURFACE

Document Type and Number:

WIPO Patent Application WO2000056444

Kind Code:

A3

Abstract:

A composition of a liquid (26) is caused to interact with a narrow band shaped area at a chosen position on a solid surface within a flow channel (12) by hydrodynamic focusing of a guided stream of said liquid between two streams of guiding liquid (28). By altering the ratio of the flow rates of the two guiding liquid streams, the position of the guided liquid stream is changed and further interaction with the solid surface takes place along a second band shaped area. Using two such flow channels it is possible to produce a two dimensional array of interaction sites.

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Inventors:

BLANKENSTEIN GERT (DE)
WEBER ANDERS (DK)
AHL THOMAS (DK)
BONDE MARTIN (DK)

Application Number:

PCT/EP2000/002578

Publication Date:

December 28, 2000

Filing Date:

March 23, 2000

Export Citation:

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Assignee:

TORSANA BIOSENSOR AS (DK)
BLANKENSTEIN GERT (DE)
WEBER ANDERS (DK)
AHL THOMAS (DK)
BONDE MARTIN (DK)

International Classes:

B01D57/02; B01F13/00; B01J19/00; B03C5/00; G01N37/00; C12M1/00; C12N15/09; F15C1/08; G01N15/14; C40B40/06; C40B60/14; (IPC1-7): B01J19/00; G01N15/14; F15C5/00; F15C1/08

Domestic Patent References:

WO1998010267A1	1998-03-12
WO1999005512A1	1999-02-04
WO1998049344A1	1998-11-05

Foreign References:

EP0916396A2

1999-05-19

Other References:

GERT BLANKENSTEIN ET AL: "MODULAR CONCEPT OF A LABORATORY ON A CHIP FOR CHEMICAL AND BIOCHEMICAL ANALYSIS", BIOSENSORS & BIOELECTRONICS, vol. 13, no. 3/04, 1998, BARKING, UK, pages 427 - 438, XP000700154, ISSN: 0956-5663
GERT BLANKENSTEIN ET AL: "FLOW SWITCH FOR ANALYTE INJECTION AND CELL/PARTICLE SORTING", ANALYTICAL METHODS AND INSTRUMENTATION, 1996, NEW YORK, US, pages 82 - 84-84, XP000865501, ISSN: 1063-5246

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