Title:
SPHINGOSINE-1-PHOSPHATE ANALOG AND SYNTHESIS METHOD THEREFOR
Document Type and Number:
WIPO Patent Application WO/2019/147092
Kind Code:
A1
Abstract:
The present specification relates to a sphingosine-1-phosphate (S1P) analog and a synthesis method therefor. A novel S1P analog according to the disclosure of the present specification has high water solubility and stability due to an alkoxyamine group. Therefore, the S1P analog is advantageous for use in fabricating a kit for immunodiagnosis.
Inventors:
KIM YONG TAE (KR)
HONG IN SUK (KR)
KIM EUN JIN (KR)
CHON CHAN HEE (KR)
CHO SEONG HWAN (KR)
HONG IN SUK (KR)
KIM EUN JIN (KR)
CHON CHAN HEE (KR)
CHO SEONG HWAN (KR)
Application Number:
PCT/KR2019/001159
Publication Date:
August 01, 2019
Filing Date:
January 28, 2019
Export Citation:
Assignee:
SEJONG BIOMED CO LTD (KR)
International Classes:
C07F9/09; G01N33/543; G01N33/544
Foreign References:
| KR20090095659A | 2009-09-09 | |||
| US20070281320A1 | 2007-12-06 | |||
| KR20140104376A | 2014-08-28 | |||
| KR101891051B1 | 2018-08-31 |
Other References:
DAI, Z. ET AL.: "Synthesis of aromatic sphingosine analogues by diastereoselective amination of enantioenriched trans-y, deltaunsaturated beta-Hydroxyesters", THE JOURNAL OF ORGANIC CHEMISTRY, vol. 79, no. 16, 2014, pages 7778 - 7784, XP055627269
ISHII, M. ET AL.: "Sphingosine-1-phosphate mobilizes osteoclast precursors and regulates bone homeostasis", NATURE, vol. 458, no. 7237, 2009, pages 524 - 529, XP002791551
ISHII, M. ET AL.: "Sphingosine-1-phosphate mobilizes osteoclast precursors and regulates bone homeostasis", NATURE, vol. 458, no. 7237, 2009, pages 524 - 529, XP002791551
Attorney, Agent or Firm:
IPS PATENT FIRM (KR)
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