Title:
SPRAY-DRYING PROCESS
Document Type and Number:
WIPO Patent Application WO/2010/111132
Kind Code:
A4
Abstract:
The process comprises delivering a spray solution comprising an active agent and a matrix material in an organic solvent to a spray-drying apparatus, atomizing the spray solution into droplets within the spray-drying apparatus to remove at least a portion of the organic solvent from the droplets to form a plurality of particles, and collecting the particles. The spray solution may be formed by forming a feed suspension comprising the active agent, the matrix material, and the organic solvent, wherein the feed suspension is at a temperature T1, and directing the feed suspension to a heat exchanger, thereby increasing the temperature of the feed suspension to a temperature T2, wherein T2 is greater than T1, and the spray solution is at a pressure greater than the vapor pressure of the organic solvent at T2, such that the active agent and matrix material are soluble in the organic solvent at T2.
Inventors:
FRIESEN DWAYNE T (US)
NEWBOLD DAVID D (US)
BAUMANN JOHN M (US)
DUBOSE DEVON B (US)
MILLARD DOUGLAS L (US)
NEWBOLD DAVID D (US)
BAUMANN JOHN M (US)
DUBOSE DEVON B (US)
MILLARD DOUGLAS L (US)
Application Number:
PCT/US2010/027930
Publication Date:
July 07, 2011
Filing Date:
March 19, 2010
Export Citation:
Assignee:
BEND RES INC (US)
FRIESEN DWAYNE T (US)
NEWBOLD DAVID D (US)
BAUMANN JOHN M (US)
DUBOSE DEVON B (US)
MILLARD DOUGLAS L (US)
FRIESEN DWAYNE T (US)
NEWBOLD DAVID D (US)
BAUMANN JOHN M (US)
DUBOSE DEVON B (US)
MILLARD DOUGLAS L (US)
International Classes:
B01J2/04
Attorney, Agent or Firm:
GARDNER, Gillian (LLPOne World Trade Center, Suite 1600,121 SW Salmon Stree, Portland OR, US)
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