Title:
STABILIZED PERTUSSIS ANTIBODIES WITH EXTENDED HALF-LIFE
Document Type and Number:
WIPO Patent Application WO/2018/035107
Kind Code:
A3
Abstract:
The present invention relates, in part, to modified humanized antibodies which bind the pertussis toxin protein and their use as therapeutic agents. In particular, the present invention is directed, in part, to improved humanized 1B7 and 11E6 antibodies with extended in vivo half-lives.
Inventors:
MAYNARD JENNIFER (US)
NGUYEN ANNALEE (US)
KALEKO MICHAEL (US)
NGUYEN ANNALEE (US)
KALEKO MICHAEL (US)
Application Number:
PCT/US2017/046917
Publication Date:
March 29, 2018
Filing Date:
August 15, 2017
Export Citation:
Assignee:
UNIV TEXAS (US)
SYNTHETIC BIOLOGICS INC (US)
SYNTHETIC BIOLOGICS INC (US)
International Classes:
A61K39/40; C07K16/12
Foreign References:
| US20150353628A1 | 2015-12-10 | |||
| US20130272964A1 | 2013-10-17 |
Attorney, Agent or Firm:
BYRD, Marshall P. (US)
Download PDF: