Title:
STABILIZED SOLID DISPERSION OF ADEFOVIR DIPIVOXIL AND PREPARATION METHOD THEREOF
Document Type and Number:
WIPO Patent Application WO/2010/032958
Kind Code:
A2
Abstract:
The present invention relates to an amorphous solid dispersion with improved stability comprising 9-[2-[[bis[(pivaloyloxy)methyl]phosphono]methoxy]ethyl] adenine which is a nucleotide analog, a pharmaceutical composition containing the same, and a preparation method for the solid dispersion.
Inventors:
LEE, Yong Tack (2-1403, Kunyoung APT. Siheung 5-dong, Geumcheon-gu, Seoul 153-035, 153-035, KR)
이용택 (서울 금천구 시흥5동 건영 APT, 153-035 Seoul, 153-035, KR)
YOON, Myeong Sik (1 Hanshin APT, 453-1 Jukjeon-dong, Suji-gu, Yongin-si, Gyeonggi-do 448-160, 448-160, KR)
윤명식 (경기도 용인시 수지구 죽전동 453-1 한신APT, 448-160 Gyeonggi-do, 448-160, KR)
HONG, Hye Suk (203 194-6, Seohyeon-dong Bundang-gu, Seongnam-si, Gyeonggi-do 463-050, 463-050, KR)
홍혜숙 (경기도 성남시 분당구 서현동 194-6 203, 463-050 Gyeonggi-do, 463-050, KR)
CHO, Il Hwan (104-102, Hangang Town APT. Gayang-dong, Gangseo-gu, Seoul 157-200, 157-200, KR)
조일환 (서울 강서구 가양동 한강타운APT. 104-102, 157-200 Seoul, 157-200, KR)
이용택 (서울 금천구 시흥5동 건영 APT, 153-035 Seoul, 153-035, KR)
YOON, Myeong Sik (1 Hanshin APT, 453-1 Jukjeon-dong, Suji-gu, Yongin-si, Gyeonggi-do 448-160, 448-160, KR)
윤명식 (경기도 용인시 수지구 죽전동 453-1 한신APT, 448-160 Gyeonggi-do, 448-160, KR)
HONG, Hye Suk (203 194-6, Seohyeon-dong Bundang-gu, Seongnam-si, Gyeonggi-do 463-050, 463-050, KR)
홍혜숙 (경기도 성남시 분당구 서현동 194-6 203, 463-050 Gyeonggi-do, 463-050, KR)
CHO, Il Hwan (104-102, Hangang Town APT. Gayang-dong, Gangseo-gu, Seoul 157-200, 157-200, KR)
조일환 (서울 강서구 가양동 한강타운APT. 104-102, 157-200 Seoul, 157-200, KR)
Application Number:
KR2009/005271
Publication Date:
March 25, 2010
Filing Date:
September 16, 2009
Export Citation:
Assignee:
CJ CHEILJEDANG CORPORATION (500 Namdaemunro 5-ga, Jung-gu, Seoul 100-749, 100-749, KR)
씨제이제일제당 (주) (서울 중구 남대문로5가 500, 100-749 Seoul, 100-749, KR)
LEE, Yong Tack (2-1403, Kunyoung APT. Siheung 5-dong, Geumcheon-gu, Seoul 153-035, 153-035, KR)
이용택 (서울 금천구 시흥5동 건영 APT, 153-035 Seoul, 153-035, KR)
YOON, Myeong Sik (1 Hanshin APT, 453-1 Jukjeon-dong, Suji-gu, Yongin-si, Gyeonggi-do 448-160, 448-160, KR)
윤명식 (경기도 용인시 수지구 죽전동 453-1 한신APT, 448-160 Gyeonggi-do, 448-160, KR)
HONG, Hye Suk (203 194-6, Seohyeon-dong Bundang-gu, Seongnam-si, Gyeonggi-do 463-050, 463-050, KR)
홍혜숙 (경기도 성남시 분당구 서현동 194-6 203, 463-050 Gyeonggi-do, 463-050, KR)
CHO, Il Hwan (104-102, Hangang Town APT. Gayang-dong, Gangseo-gu, Seoul 157-200, 157-200, KR)
씨제이제일제당 (주) (서울 중구 남대문로5가 500, 100-749 Seoul, 100-749, KR)
LEE, Yong Tack (2-1403, Kunyoung APT. Siheung 5-dong, Geumcheon-gu, Seoul 153-035, 153-035, KR)
이용택 (서울 금천구 시흥5동 건영 APT, 153-035 Seoul, 153-035, KR)
YOON, Myeong Sik (1 Hanshin APT, 453-1 Jukjeon-dong, Suji-gu, Yongin-si, Gyeonggi-do 448-160, 448-160, KR)
윤명식 (경기도 용인시 수지구 죽전동 453-1 한신APT, 448-160 Gyeonggi-do, 448-160, KR)
HONG, Hye Suk (203 194-6, Seohyeon-dong Bundang-gu, Seongnam-si, Gyeonggi-do 463-050, 463-050, KR)
홍혜숙 (경기도 성남시 분당구 서현동 194-6 203, 463-050 Gyeonggi-do, 463-050, KR)
CHO, Il Hwan (104-102, Hangang Town APT. Gayang-dong, Gangseo-gu, Seoul 157-200, 157-200, KR)
International Classes:
C07D473/32
Attorney, Agent or Firm:
AIP PATENT & LAW FIRM (Shinwon Bldg. 8F, 823-14 Yeoksam-dong, Gangnam-gu, Seoul 135-933, 135-933, KR)
Download PDF:
Previous Patent: POWER QUALITY IMPROVEMENT DEVICE AND POWER SUPPLY SYSTEM
Next Patent: SHOES WHICH ENABLE SHOE ORGANIZATION
Next Patent: SHOES WHICH ENABLE SHOE ORGANIZATION