Title:
STABLE PHARMACEUTICAL COMPOSITIONS
Document Type and Number:
WIPO Patent Application WO2003075928
Kind Code:
A3
Abstract:
Pharmaceutical compounds having the general formula: (I) or compounds having the formula: (II) Where R1 and R2 are independently H, branched or straight chain alkyl having from 1 to about 7 carbon atoms, substituted or unsubstituted cycloalkyl, substituted or unsubstituted aralkyl, substituted or unsubstituted alkylcycloalkyl, lower alkenyl or R1 and R2 together form part of a substituted or unsubstituted cycloalkyl having from about 4 of about 7 carbon atoms; where R3 is a branched or straight chain alkyl having from 1 to about 7 carbon atoms, substituted or unsubstituted aryl, substituted or unsubstituted aralkyl, substituted or unsubstituted cycloalkyl, aralkyl, substituted or unsubstituted alkylcycloalkyl or a group having the formula (CH2)nCOOH where n is from 1 to about 7.
Inventors:
BARBEAU DONALD L (US)
Application Number:
PCT/US2003/006521
Publication Date:
December 04, 2003
Filing Date:
March 04, 2003
Export Citation:
Assignee:
BARBEAU DONALD L (US)
International Classes:
A61K9/08; A61K9/48; A61K31/502; A61P9/08; A61P9/12; A61P43/00; C07D237/34; (IPC1-7): A61K31/502; C07D237/34
Domestic Patent References:
| WO2001017528A1 | 2001-03-15 |
Foreign References:
| US3840539A | 1974-10-08 |
Other References:
CLEMENTI W.A.: "Endogenous generation of hydralazine from labile hydralazine hydrazones", THE JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, vol. 222, no. 1, 1982, pages 159 - 165, XP002970837
DRUEY J. ET AL.: "Hypotensive hydrazinophthalazines and related compounds", JOURNAL OF MEDICINAL AND PHARMACEUTICAL CHEMISTRY, vol. 1, no. 1, 1959, pages 1 - 21, XP002970838
See also references of EP 1480649A4
DRUEY J. ET AL.: "Hypotensive hydrazinophthalazines and related compounds", JOURNAL OF MEDICINAL AND PHARMACEUTICAL CHEMISTRY, vol. 1, no. 1, 1959, pages 1 - 21, XP002970838
See also references of EP 1480649A4
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