STABLE SOLID DOSAGE FORMS OF AMINO ACIDS AND PROCESSES FOR PRODUCING SAME

Title:

STABLE SOLID DOSAGE FORMS OF AMINO ACIDS AND PROCESSES FOR PRODUCING SAME

Document Type and Number:

WIPO Patent Application WO2002026263

Kind Code:

A3

Abstract:

Pharmaceutical formulations, adn processes for making same, comprising an amino acid which is liable to formation of an undesirable lactam, and a stabilizer comprising a volatile alcohol; a non-volatile alcohol; a water immiscible liquid or solid; a liquid with a relatively low dielectric constant; a liquid surface active agent; a solid surface active agent; an antioxidant; a ketone, an aldehyde; a solid polyethylene glycol of high molecular weight; polyvinylpyrrolidone; a derived cellulose; silicon dioxide; or a combination thereof.

Inventors:

SPIREAS SPIRIDON (US)

Application Number:

PCT/US2001/030095

Publication Date:

January 03, 2003

Filing Date:

September 26, 2001

Export Citation:

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Assignee:

SIGMAPHARM INC (US)
SPIREAS SPIRIDON (US)

International Classes:

A61K9/16; (IPC1-7): A61K31/195; A61K9/20; A61K47/00

Domestic Patent References:

WO2001097782A1	2001-12-27
WO2001097612A1	2001-12-27
WO1999059572A1	1999-11-25
WO1999059573A1	1999-11-25
WO2000007568A1	2000-02-17
WO2001013894A1	2001-03-01

Foreign References:

EP0414263A2

1991-02-27

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