FIELD OF THE INVENTION

The present invention relates to stable oral pharmaceutical composition, in particular to compositions, which comprises taurine as active agent along with pharmaceutically acceptable excipients preferably in oral dosage form, which is useful as an energy provider booster for all age group.

BACKGROUND OF THE INVENTION

Taurine is an amino acid that supports neurological development and helps to regulate the level of water and mineral salts in the blood. Taurine is also thought to have antioxidant properties.

Some marketed taurine products are Red Bull, Bacchus Energy Drink, BSN NO-Xplode, Gaspari Nutrition, SuperPump250, Muscle Tech, Cell-Tech, Hardcore Pro Series, Double-T ,Sports CreaDyl, Muscle Tech , Nitro-Tech, Hardcore Pro Series, AllMax Nutrition Taurine, Cheap Supplements Taurine, Higher Power L-Taurine XS, NOW Taurine, NOW Taurine Double Strength, NOW Taurine Powder, PrimaForce Taurine, SciFit L-Taurine, Supplement Direct Taurine, Twinlab Mega Taurine thereof.

United States Patent 6,620,425 wherein Food supplement compositions comprise lipoic acid or a derivative thereof and creatine or a derivative thereof. The compositions optionally, but preferably, further comprise of dextrose. The food supplement compositions are suitable for supplementing the diet of an athlete and particularly for enhancing an athlete's muscle size or strength.

US Patent Application 20060094734 wherein aft alertness inducing composition contains the active ingredients caffeine and taurine and various inert substances in a dry formulation. Caffeine and taurine are delivered in an oral formulation that obviates the need for ingesting significant quantities of liquid or sugar.

l Thus, there is a need of stable taurine oral composition in the solid dosage form which can exhibited extended shelf life and can be prepared by a simple, efficient and cost effective method without using any advanced technology or high tech machinery.

SUMMARY OF THE INVENTION

In one aspect, the instant invention is to provide commercially viable and oral formulation.

In one aspect, the instant invention is to provide safe and effective dosage form with taurine composition because other ingredients which are using as energy drinks or oral formulation, with high amounts of caffeine or sugar can cause several diseases such as too much caffeine can increase heart rate and blood pressure; interrupt sleep, and cause nervousness and irritability. And added sugar may provide unwanted added calories.

In one aspect, the instant invention is to increased energy is derived from taurine then the absorption may be faster as comparative to caffeine.

In one aspect, the instant invention is to provide different release drug profile such as Sustained or controlled or retard formulation available in oral formulation (capsule, tablet, powder and in liquid thereof)

DETAILED DESCRIPTION OF THE INVENTION

The invention will now be described in detail in connection with certain preferred and optional embodiments. So that various aspects thereof may be more fully understood and appreciated.

According to the stable oral pharmaceutical composition of the present invention, the taurine is present in an amount of 1000 -1200 mg by weight. The said stable oral pharmaceutical composition is available in different drug release profiles such as Sustained or controlled or retard formulation with instant high energy booster oral dosage form such as capsule, tablet, powder and in liquid thereof.

In embodiment of the invention, the first 500 mg of Taurine will disintegrate for the immediate revitalisation and remaining 500 mg to 700mg of Taurine will be available after 12 hours.

For example the first 700 mg of Taurine will disintegrate for the immediate revitalisation and remaining 500 mg of Taurine will be available after 12 hours.

For example the first 500 mg of Taurine will disintegrate for the immediate revitalisation and remaining 700 mg of Taurine will be available after 12 hours.

In embodiment of the invention, the main active ingredient is taurine, is an amino acid. Because the human body can produce taurine on its own, this amino acid is not essential for human nutrition. However, some individuals in certain conditions (such as non-breastfed infants and people undergoing I.V. feedings) may benefit from taurine supplementation. Although this amino acid is also found in protein-rich foods. In addition to serving as a building block for making proteins, taurine may have several different roles in the human body. It acts as an antioxidant, and helps prevent macular degeneration and other serious eye diseases. It reduces blood pressure and cholesterol level, thus, helps to prevent arteriosclerosis. It improves detoxification function of the liver. It helps to strengthen the heart muscle, thus, stabilizing the function of the heart. It lessens the accumulation of lactic acid which becomes the cause of fatigue.

In embodiment of the invention, taurine improves glucose tolerance wherein Taurine works by increasing the action of insulin, improving glucose tolerance and enhancing antioxidant levels which are important functions to balance the negative effects of high sugar diets. In embodiment of the invention, taurine decreases risk of muscle damage wherein large amounts of taurine are also found in muscle, where it is believed to play an essential role. Taurine has shown the ability to lower muscle damage from intense exercise, and improve performance. Exercise depletes the muscles of taurine, making supplementation essential for anyone concerned with getting the maximum benefit from their exercise program.

In embodiment of the invention, Taurine is also used to help improve mental performance and is a common ingredient in energy drinks. Taurine is essential for proper development and growth such as Sports person and Growing /School going Children who needs instant energy thereof.

Those Patients are also able to getting energy instantly who suffered from chronic illness, Malnutrition, Long term drug therapy (cardiac, diabetic, Diabetic Condition anti tubercular and corticosteroids), Lethargy, Poor appetite thereof.

This type of supplementation may also be beneficial for the treatment in various diseases for example hypertension, congestive heart failure and diabetes,Congestive heart failure (CHF) ,Hepatitis ,Steatorrhea (fatty, frothy stools) in people with cystic fibrosis ,High blood pressure (hypertension) ,High cholesterol ,Seizures (epilepsy) ,Autism ,Attention deficit hyperactivity disorder (ADHD) ,RetinaI degeneration (an eye condition) ,Diabetes ,Alcoholism thereof.

The main characteristic of the taurine is that it will not break or damage by heating. However, it dissolves easily in water.

In the case of Vasodilation wherein Taurine supplementation can increase secretion of nitric oxide, which dilates blood vessels and improves blood flow and delivery of oxygen to muscles. However that taurine alone can increase energy and performance.

In the case of Lower Cholesterol wherein Taurine can lower cholesterol by improving gallbladder function which can then eliminate cholesterol through bile, the taurine supplementation can reduce liver and blood cholesterol levels in the treated group.

A further benefit of taurine is that it acts an as antioxidant. Antioxidants help protect damage to cells from free radicals wherein Taurine functions as a "potent" antioxidant, wherein Free radicals attack cells in body and can cause chronic conditions such as cancer, eye disease, and possibly diabetes. As many high energy drinks contain caffeine, it may be the caffeine or the combination of caffeine, taurine and/or any other ingredients which give the energy boosting qualities.

If increased energy is derived from taurine then the absorption may be faster if it is in a drink than in food

It has been suggested that L-Taurine may play a useful role in supporting a variety of processes, including:

Protein synthesis

Cell hydration

Metabolism

Cardiac function