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Title:
STANDARD SUBSTANCE FOR PSA QUANTIFICATION, PREPARATION METHOD THEREFOR, STANDARD SOLUTION FOR PSA QUANTIFICATION, AND PSA QUANTIFICATION METHOD
Document Type and Number:
WIPO Patent Application WO/2021/111820
Kind Code:
A1
Abstract:
The present invention addresses the problem of providing: a standard substance for PSA quantification, the standard substance being designed for PSA having a specific sugar chain, having less bias in sugar chain expression patterns, ensuring high production reproducibility, and being capable of versatile PSA quantification that even enables quantification of high-concentration samples from patients; a preparation method therefor; a standard solution for PSA quantification; and a PSA quantification method.　This standard substance for PSA quantification is used to quantitatively analyze prostate-specific antigen (hereinafter referred to as "PSA") having a specific sugar chain and is characterized by: having a PSA structure having a sugar chain of a sequence represented by any of structural formulae A to D; and being a compound isolated or purified from a natural product, a compound chemically or enzymatically modified from a natural product, or an artificially synthesized compound.

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Inventors:
KANEKO TOMONORI (JP)
KAYA TAKATOSHI (JP)
OTANI MAKIKO (JP)
Application Number:
PCT/JP2020/041874
Publication Date:
June 10, 2021
Filing Date:
November 10, 2020
Export Citation:
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Assignee:
KONICA MINOLTA INC (JP)
International Classes:
C07K14/42; C07K16/40; C12Q1/37; G01N33/50; G01N33/531; G01N33/543; G01N33/574
Foreign References:
JP2013076666A2013-04-25
JP2013238614A2013-11-28
JP2004239880A2004-08-26
JP2015006174A2015-01-15
JP2013076666A2013-04-25
US6406297B12002-06-18
US6221604B12001-04-24
US5994063A1999-11-30
US5808044A1998-09-15
US5880287A1999-03-09
US5556959A1996-09-17
US5135717A1992-08-04
Other References:
NARIMATSU HISASHI: "Development of basic tools for glycomics and its application to comprehensive discovery of glycol-biomarkers", JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE, vol. 225, no. 8, 24 May 2008 (2008-05-24), JP , pages 623 - 628, XP009537568, ISSN: 0039-2359
See also references of EP 4079752A4
Attorney, Agent or Firm:
KOYO INTERNATIONAL PATENT FIRM (JP)
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