Title:
STEM CELL INVASION INHIBITOR
Document Type and Number:
WIPO Patent Application WO/2004/108129
Kind Code:
A1
Abstract:
It is intended to provide an inhibitor of the invasion of bone marrow-origin vascular stem cells or inflammatory cells into vessel wall, a blood vessel restenosis inhibitor and a preventive or a remedy for angitis or carditis, each containing a phthalein pigment compound as the active ingredient; an instrument for treating blood vessels which is coated with a resin containing a phthalein pigment compound or made of this resin, and so on. By using such a drug as described above, the restenosis of a blood vessel occurring after angiogenesis, etc. can be effective prevented. Moreover, it is possible thereby to prevent the progress and breakage of a lesion of angitis, carditis or arteriosclerosis, for which no efficacious preventive or therapeutic method has been established so far, microvascular ischemic diseases, etc. By performing a medical treatment such as angiogenesis with the use of the above-described instrument for treating blood vessels, the occurrence of blood vascular restenosis can be effectively prevented.
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Inventors:
UCHIDA YASUMI (JP)
UCHIDA HARUKO (JP)
UCHIDA HARUKO (JP)
Application Number:
PCT/JP2003/007264
Publication Date:
December 16, 2004
Filing Date:
June 09, 2003
Export Citation:
Assignee:
CARDIOVASCULAR INST LTD (JP)
UCHIDA YASUMI (JP)
UCHIDA HARUKO (JP)
UCHIDA YASUMI (JP)
UCHIDA HARUKO (JP)
International Classes:
A61F2/945; A61K31/343; A61K31/39; A61L31/10; A61L31/16; A61P9/00; A61P9/10; A61P27/02; A61P37/06; A61P43/00; C07D327/04; (IPC1-7): A61K31/39; A61K45/00; A61K31/343; A61P9/00; A61P9/10; A61P27/02; A61P37/06; A61P43/00; A61L27/14; A61L27/28; A61L31/04; A61L31/08
Domestic Patent References:
| WO2001093871A1 | 2001-12-13 | |||
| WO1991003226A2 | 1991-03-21 |
Foreign References:
| EP1291026A2 | 2003-03-12 | |||
| EP0354714A2 | 1990-02-14 | |||
| US6020374A | 2000-02-01 |
Attorney, Agent or Firm:
The, Patent Corporate Body Aruga Patent Office (3-6 Nihonbashiningyocho 1-Chom, Chuo-ku Tokyo, JP)
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