Title:
STEM CELL PROLIFERATION PROMOTER
Document Type and Number:
WIPO Patent Application WO/2023/100691
Kind Code:
A1
Abstract:
The present disclosure relates to providing a substance and a composition that promote the proliferation of epidermal stem cells and are effective in improving wrinkles and barrier function from the viewpoint of maintaining or improving quality of life (QOL) in terms of both health and beauty. More specifically, a composition including 1-(2-hydroxyethyl)-2-imidazolidinone (HEI) or a derivative thereof and a seaweed extract such as Marinwort IPC-12 AGS can be used to promote the proliferation of epidermal stem cells and obtain a beneficial effect on wrinkles and barrier function.
Inventors:
IRIYAMA SHUNSUKE (JP)
Application Number:
PCT/JP2022/042858
Publication Date:
June 08, 2023
Filing Date:
November 18, 2022
Export Citation:
Assignee:
SHISEIDO CO LTD (JP)
International Classes:
C12N5/074; A61K8/49; A61K8/9706; A61K31/4166; A61K36/02; A61K45/00; A61P17/00; A61P43/00; A61Q19/08
Domestic Patent References:
| WO2018074606A1 | 2018-04-26 |
Foreign References:
| JP2007204449A | 2007-08-16 | |||
| JP2013510147A | 2013-03-21 |
Other References:
CHEN YANHUI, CHEN YING, HUANG LIYONG, YU JIANBIN: "Evaluation of heparanase and matrix metalloproteinase-9 in patients with cutaneous malignant melanoma", JOURNAL OF DERMATOLOGY, JAPANESE DERMATOLOGICAL ASSOCIATION, TOKYO., JP, vol. 39, no. 4, 1 April 2012 (2012-04-01), JP , pages 339 - 343, XP093069914, ISSN: 0385-2407, DOI: 10.1111/j.1346-8138.2011.01441.x
Attorney, Agent or Firm:
ITO Katsuhiro et al. (JP)
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