Title:
STEREOSELECTIVE SYNTHESIS OF A 4,4-DISUBSTITUTED CYCLOHEXANEPROPANOIC ACID
Document Type and Number:
WIPO Patent Application WO2005080309
Kind Code:
A8
Abstract:
There is provided a stereoselective route to a compound of formula (1): wherein R represents H or an alkali metal, Ar<1> represents 4-chlorophenyl and Ar<2> represents 2,5-difluorophenyl.
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Inventors:
BRANDS KAREL MARIE JOSEPH (US)
BREWER SARAH ELIZABETH (GB)
DAVIES ANTONY JOHN (GB)
DOLLING ULF H (US)
HAMMOND DEBORAH CAMILLE (GB)
LIEBERMAN DAVID ROSS (GB)
SCOTT JEREMY PETER (GB)
BREWER SARAH ELIZABETH (GB)
DAVIES ANTONY JOHN (GB)
DOLLING ULF H (US)
HAMMOND DEBORAH CAMILLE (GB)
LIEBERMAN DAVID ROSS (GB)
SCOTT JEREMY PETER (GB)
Application Number:
PCT/GB2005/000544
Publication Date:
November 03, 2005
Filing Date:
February 16, 2005
Export Citation:
Assignee:
MERCK SHARP & DOHME (GB)
MERCK & CO INC (US)
BRANDS KAREL MARIE JOSEPH (US)
BREWER SARAH ELIZABETH (GB)
DAVIES ANTONY JOHN (GB)
DOLLING ULF H (US)
HAMMOND DEBORAH CAMILLE (GB)
LIEBERMAN DAVID ROSS (GB)
SCOTT JEREMY PETER (GB)
MERCK & CO INC (US)
BRANDS KAREL MARIE JOSEPH (US)
BREWER SARAH ELIZABETH (GB)
DAVIES ANTONY JOHN (GB)
DOLLING ULF H (US)
HAMMOND DEBORAH CAMILLE (GB)
LIEBERMAN DAVID ROSS (GB)
SCOTT JEREMY PETER (GB)
International Classes:
C07C51/353; C07C51/60; C07C53/23; C07C57/62; C07C59/56; C07C315/02; C07C319/14; C07C319/16; C07C317/44; C07C323/61; (IPC1-7): C07C51/353; C07C53/23; C07C59/56; C07C319/14; C07C319/16; C07C323/61; C07C315/02; C07C317/44
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