Title:
STEROID COMPOUND COMBINED WITH POLYSACCHARIDE
Document Type and Number:
WIPO Patent Application WO/1992/020699
Kind Code:
A1
Abstract:
A compound which can maintain a blood steroid level unchanged for long after administration, obtained by combining a steroid derivative with a polysaccharide directly or via a spacer. Desirable examples of the steroid derivative include ones having carboxyl and/or hydroxyl groups, and those of the spacer include polybasic carboxylic acids, while those of the polysaccharide include water-soluble ones such as dextran. When administered, the compound releases the steroid in the blood and the steroid level is kept constant for long.
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Inventors:
TSUDA TOSHIRO (JP)
WATANABE SUMIO (JP)
WATANABE SUMIO (JP)
Application Number:
PCT/JP1992/000638
Publication Date:
November 26, 1992
Filing Date:
May 18, 1992
Export Citation:
Assignee:
EISAI CO LTD (JP)
International Classes:
A61K31/57; A61K47/48; C07J17/00; (IPC1-7): C07J17/00
Foreign References:
JPS6246555A | 1987-02-28 | |||
JPS5522616A | 1980-02-18 | |||
JPS5883699A | 1983-05-19 | |||
JPS62123196A | 1987-06-04 |
Other References:
See also references of EP 0540751A4
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