STEROID COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF

WIPO Patent Application WO/2023/143400

A1

Provided are a steroid compound, a preparation method therefor and a use thereof. The steroid compound may have a structure as shown in formula VI. The compound has SREBP pathway inhibitory activity, and can be used for preventing and/or treating diseases such as obesity, hyperlipidemia, fatty liver, diabetes, atherosclerosis, cardiovascular and cerebrovascular diseases, liver cancer, and skin injury.

JPS61502468	[Title of the Invention] N-substitution butyl amide derivative
WO/2001/049704	COMPOUND (I), A METHOD FOR EXTRACTING IT AND A PHARMACEUTICAL COMPOSITION CONTAINING IT
JP2972060	[Title of Invention] Cholesteric boronic acid that can be used for separation and analysis of saccharides.

LIU JINBIAO (CN)
TANG JINGJIE (CN)

PCT/CN2023/073237

August 03, 2023

January 19, 2023

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CHOLESGEN SHANGHAI CO LTD (CN)

C07J9/00; A61K31/575; A61P3/06; A61P3/10; A61P9/00; A61P9/10; A61P35/00; C07J31/00; C07J41/00

JPS61172895A	1986-08-04
CN109833319A	2019-06-04
CN104873525A	2015-09-02

SONODA, YOSHIKO ET AL.: "In Vitro Effects of Oxygenated Lanosterol Derivatives on Cholesterol Biosynthesis from 24, 25-Dihydrolanosterol", CHEM. PHARM. BULL., vol. 36, no. 3, 31 December 1988 (1988-12-31), pages 966 - 973, XP008054421
SAGIMORI, IKUYA: "Luciferase-based HMG-CoA reductase degradation assay for activity and selectivity profiling of oxy(lano)sterols", BIOORGANIC & MEDICINAL CHEMISTRY, vol. 28, 30 December 2019 (2019-12-30), XP085979639, DOI: 10.1016/j.bmc.2019.115298

SHANGHAI BESHINING LAW OFFICE (CN)

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