Title:
STEROIDAL COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/030332
Kind Code:
A1
Abstract:
A steroidal compound, a preparation method therefor and an application thereof. On one hand, provided are a compound represented by formula I, a preparation method therefor, and an application thereof in a method for separating and purifying lanosterol; on the other hand, provided is the method for separating and purifying lanosterol. The method is simple to operate, stable in process, high in productivity and low in cost, and the obtained lanosterol has high purity and can meet medical application thereof.
Inventors:
YU CHUILIANG (CN)
LI XIAOLIN (CN)
WANG YANDONG (CN)
LAN XIAOBING (CN)
HAO FEI (CN)
SU YINGXUE (CN)
HE HAIYING (CN)
WU MEIRONG (CN)
LI XIAOLIN (CN)
WANG YANDONG (CN)
LAN XIAOBING (CN)
HAO FEI (CN)
SU YINGXUE (CN)
HE HAIYING (CN)
WU MEIRONG (CN)
Application Number:
PCT/CN2022/115896
Publication Date:
March 09, 2023
Filing Date:
August 30, 2022
Export Citation:
Assignee:
GUANGZHOU OCUSUN OPHTHALMIC BIOTECHNOLOGY CO LTD (CN)
OCUSUN OPHTHALMIC PHARMACEUTICAL GUANGZHOU CO LTD (CN)
OCUSUN OPHTHALMIC PHARMACEUTICAL GUANGZHOU CO LTD (CN)
International Classes:
C07J9/00
Domestic Patent References:
| WO2021194244A1 | 2021-09-30 |
Foreign References:
| CN114591389A | 2022-06-07 | |||
| CN108929363A | 2018-12-04 | |||
| CN108884126A | 2018-11-23 | |||
| CN105377372A | 2016-03-02 | |||
| CN105017367A | 2015-11-04 | |||
| CN202111013742A | 2021-08-31 | |||
| CN101691391A | 2010-04-07 |
Other References:
ZHANG, XINGHUA: "Process for Extracting Cholesterol from Lanolin", MASTER'S THESIS, 1 June 2010 (2010-06-01), CN, pages 1 - 83, XP009543988
ISIDOROV, V.A. ; SZCZEPANIAK, L.: "Gas chromatographic retention indices of biologically and environmentally important organic compounds on capillary columns with low-polar stationary phases", JOURNAL OF CHROMATOGRAPHY A, vol. 1216, no. 51, 18 December 2009 (2009-12-18), AMSTERDAM, NL, pages 8998 - 9007, XP026783930, ISSN: 0021-9673, DOI: 10.1016/j.chroma.2009.10.079
CHING JIANHONG, SOH WEI-LI, TAN CHAY-HOON, LEE JUN-FENG, TAN JIUN-YU CHRISTINA, YANG JUN, YAP CHUN-WEI, KOH HWEE-LING: "Identification of active compounds from medicinal plant extracts using gas chromatography-mass spectrometry and multivariate data analysis", JOURNAL OF SEPARATION SCIENCE, vol. 35, no. 1, 1 January 2012 (2012-01-01), DE , pages 53 - 59, XP093041412, ISSN: 1615-9306, DOI: 10.1002/jssc.201100705
ISIDOROV, V.A. ; SZCZEPANIAK, L.: "Gas chromatographic retention indices of biologically and environmentally important organic compounds on capillary columns with low-polar stationary phases", JOURNAL OF CHROMATOGRAPHY A, vol. 1216, no. 51, 18 December 2009 (2009-12-18), AMSTERDAM, NL, pages 8998 - 9007, XP026783930, ISSN: 0021-9673, DOI: 10.1016/j.chroma.2009.10.079
CHING JIANHONG, SOH WEI-LI, TAN CHAY-HOON, LEE JUN-FENG, TAN JIUN-YU CHRISTINA, YANG JUN, YAP CHUN-WEI, KOH HWEE-LING: "Identification of active compounds from medicinal plant extracts using gas chromatography-mass spectrometry and multivariate data analysis", JOURNAL OF SEPARATION SCIENCE, vol. 35, no. 1, 1 January 2012 (2012-01-01), DE , pages 53 - 59, XP093041412, ISSN: 1615-9306, DOI: 10.1002/jssc.201100705
Attorney, Agent or Firm:
SHANGHAI BESHINING LAW OFFICE (CN)
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