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Title:
STEROLS MODIFIED BY POLYETHYLENE GLYCOL, THE PREPARATION AND THE USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2008/074216
Kind Code:
A1
Abstract:
The invention provides sterols modified by polyethylene glycol represented by the following formula, the preparation and the use thereof, wherein each symbol is defined as in the description.

Inventors:
ZHANG WENFANG (CN)
Application Number:
PCT/CN2007/003585
Publication Date:
June 26, 2008
Filing Date:
December 13, 2007
Export Citation:
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Assignee:
ZHANG WENFANG (CN)
International Classes:
C07J9/00; A61K8/86; A61K47/28; A61K47/34; A61K47/48
Domestic Patent References:
WO1996011023A11996-04-18
Foreign References:
CN1962683A2007-05-16
US4971803A1990-11-20
Other References:
CORNFORTH J.W. ET AL.: "Preparation of antituberculous poly(oxyethylene ethers) of homogeneous structure", TETRAHEDRON, vol. 29, no. 11, 1973, pages 1659 - 1667
ZINGONI J. ET AL.: "Preparation of passive bilayer liposomes", CHEMISTRY AND PHYSICS OF LIPIDS, vol. 46, no. 1, 1988, pages 73 - 77, XP024783483, DOI: doi:10.1016/0009-3084(88)90116-8
PEDERSEN H.L. ET AL.: "Ligand effects on the diastereoselectivities of samarjum diiodide promoted pinacol coupling", EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, no. 3, 1999, pages 565 - 572
MENGER F.M. ET AL.: "Cytomimetic Modeling in Which One Phospholipid Liposome Chemically Attacks Another", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 122, no. 27, 2000, pages 6492 - 6493
HAI L. ET AL.: "Synthesis of amphiphilic hepatocyte targeting cholesterylated thiogalactosides", CHINESE CHEMICAL LETTERS, vol. 16, no. 8, 2005, pages 1021 - 1023
YIN H.-Q. ET AL.: "Progress in the Temperature-controlled Transition of Self Assemblies in Surfactant Solutions", vol. 21, no. 11, November 2005 (2005-11-01), pages 1324 - 1330
WU X. ET AL.: "Synthesis of cholesterylated carboxylic acids with olig(polyethylene)", LETTERS IN ORGANIC CHEMISTRY, vol. 3, no. 12, December 2006 (2006-12-01), pages 911 - 914
Attorney, Agent or Firm:
PEKSUNG INTELLECTUAL PROPERTY LTD. (ShouqiPEKSUNG INTELLECTUAL PROPERTY LTD.,908, Shining Tower, 35 Xueyuan Road,Haidian District, Beijing 3, CN)
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