STICK-SHAPED SUBSTRATE CONTAINING LIPID-PEPTIDE-TYPE COMPOUND

Title:

STICK-SHAPED SUBSTRATE CONTAINING LIPID-PEPTIDE-TYPE COMPOUND

Document Type and Number:

WIPO Patent Application WO/2016/208473

Kind Code:

A1

Abstract:

[Problem] To provide an external skin preparation solid substrate exhibiting high breaking strength and excellent thermal stability, and usable as a stick-shaped substrate or the like. [Solution] An external skin preparation solid substrate containing: a lipid-peptide-type compound comprising one or more types selected from among a compound represented by formula (1), a compound similar thereto, or a pharmaceutically usable salt thereof; a surfactant; water; and a C8-30 saturated or unsaturated monovalent alcohol. (In the formula, R1 represents a C9-23 aliphatic group, R2 represents a hydrogen atom or a C1-4 alkyl group that may have a C1 or C2 branched chain, R3 represents a -(CH2)n-X group, n represents a number from 1 to 4, and X represents an amino group, a guanidino group, a -CONH2 group, or a five-membered or six-membered ring which may have 1 to 3 nitrogen atoms or a condensed heterocycle configured from the five-membered ring and the six-membered ring.)

Inventors:

KASHINO TSUBASA (JP)
IMOTO TAKAYUKI (JP)

Application Number:

PCT/JP2016/067828

Publication Date:

December 29, 2016

Filing Date:

June 15, 2016

Export Citation:

Click for automatic bibliography generation Help

Assignee:

NISSAN CHEMICAL IND LTD (JP)

International Classes:

A61K47/42; A61K8/34; A61K8/64; A61K8/86; A61K9/06; A61K31/167; A61K31/506; A61K47/10; A61K47/12; A61K47/14; A61K47/24; A61Q1/00; A61Q19/00

Domestic Patent References:

WO2010049389A1	2010-05-06
WO2010049390A1	2010-05-06
WO2014054702A1	2014-04-10
WO2014003015A1	2014-01-03
WO2011052613A1	2011-05-05
WO2015099074A1	2015-07-02

Foreign References:

JP2015051961A

2015-03-19

Other References: