Title:
STRAPPED AND MODIFIED BIS (BENZIMIDAZOLE) DIAMIDES FOR ASYMMETRIC CATALYSTS AND OTHER APPLICATIONS
Document Type and Number:
WIPO Patent Application WO2003057667
Kind Code:
B1
Abstract:
New compounds that are similar in function to tetrapyrrole ligands are provided. The basic framework consists of three classes of homochiral cyclic bis(benzimidazole) ligands: (1) bis(benzamidazoles) having Schiff base linkages; (2) bis(benzimidazoles) with diamime linkages; and (3) bis(benzimidazoles) with diamide linkages. Complexes of these ligands are also provided. The bis(benzimidazole) ligands further comprise a strap that lessens or precludes racemization of ligands or their complexes. These homochiral ligands are useful as catalysts for many types of reactions, including asymmetric epoxidation, epoxide ring opening. Diels-Alder, hereto Diels-Alder, asymmetric oxidation of benzylic hydrocarbons, oxidation of sulfides, hydroxylation, aziridination, cyclopropanation, kinetic resolution of allenes and other cumulenes, and the addition of HCN to imines. Also provided are polymer supports comprising the homochiral bis(benzimidazole) ligands and complexes.
Inventors:
CHAN MICHAEL K (US)
FENKER THOMSZ (PL)
ZHAO GANG (US)
FENKER THOMSZ (PL)
ZHAO GANG (US)
Application Number:
PCT/US2002/041849
Publication Date:
April 08, 2004
Filing Date:
December 31, 2002
Export Citation:
Assignee:
UNIV OHIO STATE RES FOUND (US)
CHAN MICHAEL K (US)
FENKER THOMSZ (PL)
ZHAO GANG (US)
CHAN MICHAEL K (US)
FENKER THOMSZ (PL)
ZHAO GANG (US)
International Classes:
B01J31/18; C07D471/22; C07D487/14; C07D498/22; (IPC1-7): C07D225/00; C07D245/00; C07D295/00
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