Title:
STREPTOCOCCUS PYOGENES ANTIGENS
Document Type and Number:
WIPO Patent Application WO2004078907
Kind Code:
A3
Abstract:
The present invention discloses isolated nucleic acid molecules encoding a hyperimmune serum reactive antigen or a fragment thereof as well as hyperimmune serum reactive antigens or fragments thereof from S. pyogenes, methods for isolating such antigens and specific uses therefor
Inventors:
MEINKE ANDREAS (AT)
NAGY ESZTER (AT)
WINKLER BIRGIT (AT)
GELBMANN DIETER (AT)
NAGY ESZTER (AT)
WINKLER BIRGIT (AT)
GELBMANN DIETER (AT)
Application Number:
PCT/EP2004/002087
Publication Date:
March 10, 2005
Filing Date:
March 02, 2004
Export Citation:
Assignee:
INTERCELL AG (AT)
MEINKE ANDREAS (AT)
NAGY ESZTER (AT)
WINKLER BIRGIT (AT)
GELBMANN DIETER (AT)
MEINKE ANDREAS (AT)
NAGY ESZTER (AT)
WINKLER BIRGIT (AT)
GELBMANN DIETER (AT)
International Classes:
A61K39/09; C07K14/315; C07K16/12; C12N15/31; C12Q1/68; G01N33/68; A61K39/00; C12R1/46; (IPC1-7): C12N15/31; C07K14/315; C12R1/46; C07K16/12; C12Q1/68; A61K39/09; G01N33/68
Domestic Patent References:
| WO2002034771A2 | 2002-05-02 | |||
| WO2002059148A2 | 2002-08-01 |
Other References:
DATABASE EMBL 1 June 2001 (2001-06-01), FERRETTI J.J., ET AL.: "Hypothetical protein SPy0012", XP002293513, retrieved from EBI Database accession no. Q9A202
DATABASE EMBL 1 October 2002 (2002-10-01), SMOOT J.C., ET AL.: "Hypothetical protein spyM18_0011", XP002293515, retrieved from EBI Database accession no. Q8P323
DATABASE EMBL 1 October 2002 (2002-10-01), BERES S.B., ET AL: "Hypothetical protein SpyM3_0009", XP002293517, retrieved from EBI Database accession no. Q8K8Z4
HENICS T ET AL: "Small-fragment genomic libraries for the display of putative epitopes from clinically significant pathogens.", BIOTECHNIQUES, vol. 35, no. 1, July 2003 (2003-07-01), pages 196 - 209, XP002293668, ISSN: 0736-6205
REID SEAN D ET AL: "Postgenomic analysis of four novel antigens of group A Streptococcus: Growth phase-dependent gene transcription and human serologic response", JOURNAL OF BACTERIOLOGY, vol. 184, no. 22, November 2002 (2002-11-01), pages 6316 - 6324, XP002293669, ISSN: 0021-9193
REID SEAN D ET AL: "Multilocus analysis of extracellular putative virulence proteins made by group A Streptococcus: Population genetics, human serologic response, and gene transcription", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 98, no. 13, 19 June 2001 (2001-06-19), pages 7552 - 7557, XP002293670, ISSN: 0027-8424
DATABASE BIOSIS [online] BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; 2002, VANDERMEID K R ET AL: "Utilization of human antibodies to open reading frame proteins for evaluating opsonophagocytic activity against Streptococcus pyogenes", XP002293671, Database accession no. PREV200200585381
DATABASE EMBL 1 October 2002 (2002-10-01), SMOOT J.C., ET AL.: "Hypothetical protein spyM18_0011", XP002293515, retrieved from EBI Database accession no. Q8P323
DATABASE EMBL 1 October 2002 (2002-10-01), BERES S.B., ET AL: "Hypothetical protein SpyM3_0009", XP002293517, retrieved from EBI Database accession no. Q8K8Z4
HENICS T ET AL: "Small-fragment genomic libraries for the display of putative epitopes from clinically significant pathogens.", BIOTECHNIQUES, vol. 35, no. 1, July 2003 (2003-07-01), pages 196 - 209, XP002293668, ISSN: 0736-6205
REID SEAN D ET AL: "Postgenomic analysis of four novel antigens of group A Streptococcus: Growth phase-dependent gene transcription and human serologic response", JOURNAL OF BACTERIOLOGY, vol. 184, no. 22, November 2002 (2002-11-01), pages 6316 - 6324, XP002293669, ISSN: 0021-9193
REID SEAN D ET AL: "Multilocus analysis of extracellular putative virulence proteins made by group A Streptococcus: Population genetics, human serologic response, and gene transcription", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 98, no. 13, 19 June 2001 (2001-06-19), pages 7552 - 7557, XP002293670, ISSN: 0027-8424
DATABASE BIOSIS [online] BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; 2002, VANDERMEID K R ET AL: "Utilization of human antibodies to open reading frame proteins for evaluating opsonophagocytic activity against Streptococcus pyogenes", XP002293671, Database accession no. PREV200200585381
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