SUBSTANCE CAPABLE OF INHIBITING GLYCINE TRANSPORTER

WIPO Patent Application WO/2012/081665

A1

The present invention relates to a novel compound represented by formula [I] or a pharmaceutically acceptable salt thereof. This compound is useful for the prevention or treatment of diseases such as schizophrenia, Alzheimer's disease, cognitive dysfunction, dementia, anxiety disorders (generalized anxiety disorder, panic disorder, obsessive-compulsive disorder, social anxiety disorder, post-traumatic stress disorder, a specific phobia, acute stress disorder, and the like), depression, drug dependence, convulsion, tremor, pain, Parkinson's disease, attention deficit/hyperactivity disorder, bipolar disorder, eating disorder, sleep disorder and the like, of which the action relies on an inhibitory activity on the intake of glycine.

YAMAMOTO SHUJI (JP)
OHTA HIROSHI (JP)
ABE KUMI (JP)
ARAKI YUKO (JP)
MORIYA MINORU (JP)
SUN XIANG-MIN (JP)
YASUHARA AKITO (JP)

PCT/JP2011/079043

June 21, 2012

December 15, 2011

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TAISHO PHARMACEUTICAL CO LTD (JP)
YAMAMOTO SHUJI (JP)
OHTA HIROSHI (JP)
ABE KUMI (JP)
ARAKI YUKO (JP)
MORIYA MINORU (JP)
SUN XIANG-MIN (JP)
YASUHARA AKITO (JP)

A61K31/4184; C07D235/02; A61K31/422; A61K31/4439; A61K31/4545; A61K31/497; A61K31/501; A61K31/506; A61K31/5377; A61P25/00; A61P25/04; A61P25/08; A61P25/16; A61P25/18; A61P25/20; A61P25/22; A61P25/24; A61P25/28; A61P25/30; A61P43/00; C07D401/04; C07D401/14; C07D405/14; C07D413/06; C07D413/14; C07D417/14; C07D471/04

WO2009034062A1

2009-03-19

JP2010517964A	2010-05-27
JP2000507581A	2000-06-20
JP2004107323A	2004-04-08
JP2006509015A	2006-03-16

ONO, Shinjiro et al. (JP)
Ono Shinjiro (JP)

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