Title:
SUBSTITTUED PYRIDINE INHIBITORS OF HIF PROLYL HYDROXYLASE
Document Type and Number:
WIPO Patent Application WO/2016/054806
Kind Code:
A1
Abstract:
The present invention concerns compounds of formula I that inhibit HIF prolyl hydroxylase, their use for enhancing endogenous production of erythropoietin, and for treating conditions associated with reduced endogenous production of erythropoietin such as anemia and like conditions, as well as pharmaceutical compositions comprising such a compound and a pharmaceutical carrier.
Inventors:
UJJAINWALLA FEZ (US)
TAN JOHN QIANG (US)
DANG QUN (US)
SINZ CHRISTOPHER J (US)
WANG MING (US)
CHEN YILI (US)
CAI JIAQIANG (CN)
DU XIAOXING (CN)
TAN JOHN QIANG (US)
DANG QUN (US)
SINZ CHRISTOPHER J (US)
WANG MING (US)
CHEN YILI (US)
CAI JIAQIANG (CN)
DU XIAOXING (CN)
Application Number:
PCT/CN2014/088320
Publication Date:
April 14, 2016
Filing Date:
October 10, 2014
Export Citation:
Assignee:
MERCK SHARP & DOHME (US)
UJJAINWALLA FEZ (US)
TAN JOHN QIANG (US)
DANG QUN (US)
SINZ CHRISTOPHER J (US)
WANG MING (US)
CHEN YILI (US)
CAI JIAQIANG (CN)
DU XIAOXING (CN)
UJJAINWALLA FEZ (US)
TAN JOHN QIANG (US)
DANG QUN (US)
SINZ CHRISTOPHER J (US)
WANG MING (US)
CHEN YILI (US)
CAI JIAQIANG (CN)
DU XIAOXING (CN)
International Classes:
C07D213/81; A61K31/505; A61K31/506; A61K31/66; A61P7/00
Domestic Patent References:
| WO2013040789A1 | 2013-03-28 | |||
| WO2009073669A1 | 2009-06-11 | |||
| WO2012170439A1 | 2012-12-13 |
Foreign References:
| US20070299086A1 | 2007-12-27 | |||
| CN101663037A | 2010-03-03 |
Attorney, Agent or Firm:
WU, FENG & ZHANG CO. (Tower B,Beijing Aerospace Cpmiec Building,No. 30, Haidian South Road, Haidian District, Beijing 0, CN)
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