SUBSTITUTED ACRYLAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME

WIPO Patent Application WO/2006/121095

A1

A pharmaceutical composition comprising a compound having the general formula (I) or a pharmacologically acceptable salt thereof as the active ingredient: (I) wherein R¹ represents a C₆-C₁₀ aryl group which may be substituted by a residue selected from the substituent group &agr or the like; R² represents a C₆-C₁₀ aryl group which may be substituted by a residue selected from the substituent group &agr or the like; and X represents a hydroxyl group, a C₁-C₆ alkoxy group or the like.

AOKI KAZUMASA
SUDA KOJI
KANEKO TOSHIO
KIMURA TOMIO

PCT/JP2006/309445

November 16, 2006

May 11, 2006

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SANKYO CO (JP)
AOKI KAZUMASA
SUDA KOJI
KANEKO TOSHIO
KIMURA TOMIO

A61K31/166; A61K31/222; A61K31/341; A61K31/36; A61K31/381; A61K31/402; A61K31/4035; A61K31/44; A61K31/4402; A61K31/4406; A61K31/4409; A61K31/47; A61K31/495; A61K31/517; A61K31/5375; A61P1/02; A61P3/14; A61P19/02; A61P19/10; A61P29/00; A61P35/04; C07C237/22; C07C323/63; C07D207/325; C07D207/327; C07D207/404; C07D213/30; C07D213/56; C07D213/82; C07D215/14; C07D239/96; C07D277/64; C07D295/08; C07D295/14; C07D295/18; C07D307/22; C07D307/66; C07D309/06; C07D317/58; C07D319/20; C07D333/16; C07D333/20

WO2004002977A1

2004-01-08

JP2001506965A	2001-05-29
JPS63166851A	1988-07-11
JP2000204071A	2000-07-25
US20050250819A1	2005-11-10
JP2000510098A	2000-08-08

TOPUZYAN V.O. ET AL.: "Synthesis and biological properties of N-substituted alpha,beta-dehydrodipeptides", KHIMIKO-FARMATSEVTICHESKII ZHURNAL, vol. 29, no. 3, 1995, pages 42 - 44, XP008065293
See also references of EP 1880720A4

Yaguchi, Toshiaki c/o DAIICHI SANKYO COMPANY (LIMITED 1-16-13, Kitakasai, Edogawa-k, Tokyo ., JP)

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