Title:
SUBSTITUTED AMINOQUINAZOLINE COMPOUND, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2019/223671
Kind Code:
A1
Abstract:
The present invention relates to a substituted aminoquinazoline compound, and a pharmaceutical composition and a use thereof. The aminoquinazoline compound is a compound represented by formula (I), or a pharmaceutically acceptable salt thereof, a prodrug, a hydrate or a solvent compound, a crystal form, a stereoisomer or an isotope variant. The compound and the composition can be used for treating and/or preventing ErbB family tyrosine kinase mediated diseases.
Inventors:
WANG YIHAN (CN)
REN XINGYE (CN)
REN XINGYE (CN)
Application Number:
PCT/CN2019/087720
Publication Date:
November 28, 2019
Filing Date:
May 21, 2019
Export Citation:
Assignee:
SHENZHEN TARGETRX INC (CN)
International Classes:
C07D401/12; A61K31/517; A61P35/00; C07D403/12
Domestic Patent References:
| WO2015154725A1 | 2015-10-15 |
Foreign References:
| CN101679384A | 2010-03-24 |
Other References:
WANG, WENFENG ET AL.: "Application of Deuteration in Drug Research", QILU PHARMACEUTICAL AFFAIRS, vol. 29, no. 11, 10 August 3113 (3113-08-10), pages 682, XP008173943
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