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Title:
SUBSTITUTED AZOLE COMPOUND AND THERAPEUTIC AGENT FOR DIABETES
Document Type and Number:
WIPO Patent Application WO/2015/170775
Kind Code:
A1
Abstract:
[Problem] To provide a novel substituted azole compound having a GPR119-activating activity and useful particularly for the prevention and/or treatment of diabetes and obesity. [Solution] Provided are: a novel substituted azole compound represented by formula (I) (wherein each substituent is as defined in detail in the description; the ring A represents an aromatic ring which may be substituted by a substituent as defined in the description; the ring B represents a ring selected from rings represented by formula (II); R1 represents a hydrogen atom, an alkyl group or the like; R2 represents an alkyl group or the like; the ring C represents a benzene ring, a 5- to 6-membered aromatic heterocyclic ring or the like; and R3 and R4 independently represent an alkyl group which may be substituted or the like), a tautomer or pharmaceutically acceptable salt of the compound, or a solvate of the compound or the tautomer or pharmaceutically acceptable salt.

Inventors:
SHINTANI YUSUKE (JP)
NIWA MASATOSHI (JP)
MONMA SOUICHI (JP)
ISHIYAMA SEISHI (JP)
SHIGETA YUKIHIRO (JP)
KAMIYAMA TOSHIHIKO (JP)
SHIMAZAWA YOSHINOBU (JP)
OKADA KAZUAKI (JP)
Application Number:
PCT/JP2015/063525
Publication Date:
November 12, 2015
Filing Date:
May 11, 2015
Export Citation:
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Assignee:
NISSAN CHEMICAL IND LTD (JP)
International Classes:
C07D231/12; A61K31/415; A61K31/42; A61K31/425; A61K31/4439; A61P3/10; A61P43/00; C07D261/08; C07D275/02; C07D401/12; C07D413/12; C07D417/12; C07D417/14; C07D471/04
Domestic Patent References:
WO2012050151A12012-04-19
WO2013018675A12013-02-07
WO2013108800A12013-07-25
WO2011016469A12011-02-10
Foreign References:
JP2010533721A2010-10-28
JP2011516428A2011-05-26
JP2013543885A2013-12-09
JP2012528847A2012-11-15
JP2005536494A2005-12-02
Attorney, Agent or Firm:
HANABUSA PATENT & TRADEMARK OFFICE (JP)
A patent business corporation is a なぶさ patent trademark office. (JP)
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