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Patent Searching and Data


Title:
SUBSTITUTED BIPHENYL COMPOUND AND PHARMACEUTICAL COMPOSITION THEREOF
Document Type and Number:
WIPO Patent Application WO/2017/152755
Kind Code:
A1
Abstract:
The present invention provides a substituted biphenyl compound and a pharmaceutical composition thereof, the substituted biphenyl compound being a compound represented by formula (I), or a crystal form, a pharmaceutically acceptable salt, a prodrug, a stereoisomer, a hydrate or a solvent compound thereof. The compound in the present invention has a better neprilysin inhibitory activity, better performance in pharmacodynamics/pharmacokinetics, good applicability and high safety, can be used in the preparation of drugs for treating diseases related to neprilysin, and has a good market development prospect.

Inventors:
WANG YIHAN (CN)
ZHAO JIUYANG (CN)
Application Number:
PCT/CN2017/074368
Publication Date:
September 14, 2017
Filing Date:
February 22, 2017
Export Citation:
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Assignee:
SHENZHEN TARGETRX INC (CN)
International Classes:
C07C233/47; A61K31/216; A61P9/04; A61P9/12
Domestic Patent References:
WO2016037098A12016-03-10
Foreign References:
CN103313708A2013-09-18
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