Title:
SUBSTITUTED FUSED HETEROCYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/116594
Kind Code:
A1
Abstract:
A substituted fused heterocyclic compound, and a preparation method therefor and the use thereof. Provided is a compound having the structure of formula (I) or a pharmaceutically acceptable salt thereof. The compound or the pharmaceutically acceptable salt thereof can be used as an ATR inhibitor, which has a high activity.
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Inventors:
LONG KAI (CN)
Application Number:
PCT/CN2022/139864
Publication Date:
June 29, 2023
Filing Date:
December 19, 2022
Export Citation:
Assignee:
SHANGHAI ANNOVA BIOTECHNOLOGY CO LTD (CN)
International Classes:
A61K31/5377; C07D471/04; A61P35/00; A61P35/02; C07D473/34; C07D487/04; C07D519/00
Foreign References:
| CN103068391A | 2013-04-24 | |||
| CN102850355A | 2013-01-02 | |||
| CN111205310A | 2020-05-29 | |||
| US20110257170A1 | 2011-10-20 |
Other References:
BARSANTI PAUL A, PAN YUE, LU YIPIN, JAIN RAMA, COX MATTHEW, AVERSA ROBERT J., DILLON MICHAEL P., ELLING ROBERT, HU CHENG, JIN XIAN: "Structure-Based Drug Design of Novel, Potent, and Selective Azabenzimidazoles (ABI) as ATR Inhibitors", ACS MEDICINAL CHEMISTRY LETTERS, AMERICAN CHEMICAL SOCIETY, US, vol. 6, no. 1, 8 January 2015 (2015-01-08), US , pages 42 - 46, XP093073759, ISSN: 1948-5875, DOI: 10.1021/ml500352s
Attorney, Agent or Firm:
BEIJING SANYOU INTELLECTUAL PROPERTY AGENCY LTD. (CN)
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