SUBSTITUTED HETEROARYL COMPOUND, COMPOSITION CONTAINING SAME, AND APPLICATION THEREOF

Title:

SUBSTITUTED HETEROARYL COMPOUND, COMPOSITION CONTAINING SAME, AND APPLICATION THEREOF

Document Type and Number:

WIPO Patent Application WO/2017/143836

Kind Code:

A1

Abstract:

Provided in the present invention are a substituted heteroaryl compound, a composition containing same, and an application thereof, the present invention disclosing a heteroaryl compound of the formula (I), or a crystalline form, a pharmaceutically acceptable salt, a prodrug, a stereoisomer, a hydrate, or a solvent compound thereof. The substituted heteroaryl compound and the composition containing same set forth in the present invention can be used for regulating hypoxia inducible factor (HIF) and/or endogenous erythropoietin (EPO), simultaneously having better pharmacokinetic parameter characteristics and being able to improve the drug concentration of the compound in animal bodies, in order to improve the curative effect and safety of the drug.

Inventors:

WANG YIHAN (CN)
REN XINGYE (CN)

Application Number:

PCT/CN2016/109673

Publication Date:

August 31, 2017

Filing Date:

December 13, 2016

Export Citation:

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Assignee:

SHENZHEN TARGETRX INC (CN)

International Classes:

C07D217/26; A61K31/438; A61P1/16; A61P7/06; A61P9/10; A61P11/00; A61P17/02; A61P25/08; A61P25/28

Foreign References:

CN1816527A	2006-08-09
CN106083720A	2016-11-09

Other References: