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Title:
SUBSTITUTED IMIDAZO[1,2-B]PYRIDAZINES
Document Type and Number:
WIPO Patent Application WO/2012/013713
Kind Code:
A3
Abstract:
The invention relates to imidazo[1,2-b]pyridazines of general formula (I) a process for their manufacuture and their use for the treatment of benign and malignant neoplasia.

Inventors:
REHWINKEL HARTMUT (DE)
HAEGEBARTH ANDREA (DE)
POLITZ OLIVER (DE)
NEUHAUS ROLAND (DE)
BOEMER ULF (DE)
Application Number:
PCT/EP2011/062927
Publication Date:
April 12, 2012
Filing Date:
July 27, 2011
Export Citation:
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Assignee:
BAYER PHARMA AG (DE)
REHWINKEL HARTMUT (DE)
HAEGEBARTH ANDREA (DE)
POLITZ OLIVER (DE)
NEUHAUS ROLAND (DE)
BOEMER ULF (DE)
International Classes:
C07D487/04; A61K31/5025
Domestic Patent References:
WO2008052734A12008-05-08
WO2010114780A12010-10-07
Foreign References:
US20090318410A12009-12-24
Other References:
KATE F BYTH ET AL: "Imidazo[1,2-b]pyridazines: a potent and selective class of cyclin-dependent kinase inhibitors", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, PERGAMON, ELSEVIER SCIENCE, GB, vol. 14, no. 9, 3 May 2004 (2004-05-03), pages 2249 - 2252, XP002567211, ISSN: 0960-894X, [retrieved on 20040305], DOI: 10.1016/J.BMCL.2004.02.008
Attorney, Agent or Firm:
BAYER PHARMA AKTIENGESELLSCHAFT (Patents and LicensingMüllerstrasse 178, Berlin, DE)
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