Title:
SUBSTITUTED N-ARYLHETEROCYCLES, METHOD FOR PRODUCTION AND USE THEREOF AS MEDICAMENTS
Document Type and Number:
WIPO Patent Application WO2004072025
Kind Code:
A3
Abstract:
The invention relates to N-arylheterocycles and the physiologically-acceptable salts and physiologically-functional derivatives thereof. Compounds of formula (I), where the groups have the given meanings, the N-oxides and the physiologically-acceptable salts and methods for production thereof are disclosed. The compounds are suitable as anorectics for example.
Inventors:
SCHWINK LOTHAR
STENGELIN SIEGFRIED
GOSSEL MATTHIAS
BOEHME THOMAS
HESSLER GERHARD
STAHL PETRA
GRETZKE DIRK
STENGELIN SIEGFRIED
GOSSEL MATTHIAS
BOEHME THOMAS
HESSLER GERHARD
STAHL PETRA
GRETZKE DIRK
Application Number:
PCT/EP2004/001342
Publication Date:
December 23, 2004
Filing Date:
February 13, 2004
Export Citation:
Assignee:
AVENTIS PHARMA GMBH (DE)
International Classes:
A61P3/00; C07D205/04; C07D207/14; C07D207/16; C07D207/26; C07D207/34; C07D211/58; C07D401/04; C07D401/12; C07D401/14; C07D403/12; C07D405/12; C07D405/14; C07D409/12; C07D413/12; C07D417/12; (IPC1-7): C07D207/14; C07D205/04; C07D207/16; C07D207/26; C07D207/34; C07D211/58; C07D401/04; C07D401/12; C07D401/14; C07D403/12; C07D405/12; C07D405/14; C07D409/12; C07D413/12; C07D417/12
Domestic Patent References:
| WO2002099388A2 | 2002-12-12 | |||
| WO2000071529A1 | 2000-11-30 | |||
| WO2000061569A1 | 2000-10-19 | |||
| WO2002006232A1 | 2002-01-24 | |||
| WO2002042271A2 | 2002-05-30 | |||
| WO2002020501A2 | 2002-03-14 | |||
| WO2002006278A1 | 2002-01-24 | |||
| WO1996013502A1 | 1996-05-09 | |||
| WO1999024406A1 | 1999-05-20 | |||
| WO2004002948A1 | 2004-01-08 | |||
| WO2002010146A1 | 2002-02-07 |
Foreign References:
| EP1176140A1 | 2002-01-30 |
Other References:
DATABASE CAPLUS [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; ANNAKA, MASAYUKI ET AL: "Preparation of phenylcarboxamides with activity of suppressing secretion of apolipoprotein B", XP002283877, retrieved from STN Database accession no. 2002:946281
DATABASE CAPLUS [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; ANNAKA, MASAYUKI ET AL: "Preparation of biphenylcarboxamides as apolipoprotein B secretion inhibitors and hypolipemics", XP002301820, retrieved from STN Database accession no. 2002:946251
DATABASE CAPLUS [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; NAITO, YOICHIRO ET AL: "Preparation of N-[(hydroxypiperidinyl)phenyl]benzamides as pharmaceuticals for treatment of atopic dermatitis, asthma, and allergic rhinitis", XP002301821, retrieved from STN Database accession no. 2002:900790
WOOD, MICHAEL R. ET AL: "Benzodiazepines as Potent and Selective Bradykinin B1 Antagonists", JOURNAL OF MEDICINAL CHEMISTRY , 46(10), 1803-1806 CODEN: JMCMAR; ISSN: 0022-2623, 2003, XP002301819
DATABASE CAPLUS [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; SENO, KAORU ET AL: "Preparation of pyrazolo[1,5-a]pyrimidine derivatives as NAD(P)H oxidase inhibitors", XP002301822, retrieved from STN Database accession no. 2003:875291
DATABASE CAPLUS [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; ANNAKA, MASAYUKI ET AL: "Preparation of biphenylcarboxamides as apolipoprotein B secretion inhibitors and hypolipemics", XP002301820, retrieved from STN Database accession no. 2002:946251
DATABASE CAPLUS [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; NAITO, YOICHIRO ET AL: "Preparation of N-[(hydroxypiperidinyl)phenyl]benzamides as pharmaceuticals for treatment of atopic dermatitis, asthma, and allergic rhinitis", XP002301821, retrieved from STN Database accession no. 2002:900790
WOOD, MICHAEL R. ET AL: "Benzodiazepines as Potent and Selective Bradykinin B1 Antagonists", JOURNAL OF MEDICINAL CHEMISTRY , 46(10), 1803-1806 CODEN: JMCMAR; ISSN: 0022-2623, 2003, XP002301819
DATABASE CAPLUS [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; SENO, KAORU ET AL: "Preparation of pyrazolo[1,5-a]pyrimidine derivatives as NAD(P)H oxidase inhibitors", XP002301822, retrieved from STN Database accession no. 2003:875291
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