Title:
SUBSTITUTED PHENOXYACETIC ACIDS
Document Type and Number:
WIPO Patent Application WO2001000566
Kind Code:
A3
Abstract:
Disclosed are substituted phenoxyacetic acids useful in the treatment of chronic complications arising from diabetes mellitus. Also disclosed are pharmaceutical compositions containing the compounds, alone or in combination with other therapeutic agents, and methods of treatment employing the compounds and pharmaceutical compositions, as well as methods for their synthesis.
Inventors:
VAN ZANDT MICHAEL C (US)
Application Number:
PCT/US2000/017377
Publication Date:
February 07, 2002
Filing Date:
June 23, 2000
Export Citation:
Assignee:
INST FOR PHARM DISCOVERY INC (US)
ZANDT MICHAEL C VAN (US)
ZANDT MICHAEL C VAN (US)
International Classes:
A61K31/165; A61K31/166; A61K31/192; A61K31/195; A61K31/196; A61K31/216; A61K31/275; A61K31/36; A61K31/40; A61K31/401; A61K31/403; A61K31/407; A61K31/428; A61K31/44; A61K31/472; C07D295/14; A61K31/536; A61K31/5375; A61K31/55; A61K31/551; A61K45/00; A61P3/00; A61P3/10; A61P25/00; C07C235/60; C07C237/44; C07C255/57; C07C317/46; C07C323/62; C07C323/63; C07C327/48; C07D265/26; C07D277/64; C07D277/82; C07D295/155; C07D317/58; (IPC1-7): C07C235/60; C07D317/58; C07C323/62; C07C327/48; C07C317/46; C07D277/64; A61K31/166; A61K31/428; C07C255/57; A61P3/00; C07C237/44; C07D295/14; A61K38/55; A61K31/425; A61P3/10
Domestic Patent References:
| WO1996041795A1 | 1996-12-27 | |||
| WO1986005779A1 | 1986-10-09 | |||
| WO1994008945A1 | 1994-04-28 |
Foreign References:
| JPS436936B1 | ||||
| US5399703A | 1995-03-21 |
Other References:
DRAIN, D. J. ET AL: "Effects of substituting tetrazole for carboxyl in two series of antiinflammatory phenoxyacetic acids", J. PHARM., PHARMACOL., vol. 23, no. 11, 1971, pages 857 - 864, XP000964534
DATABASE CHEMABS [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; CHEN, JICHOU ET AL: "Synthesis of carboxyphenoxyacetic acid derivatives using liquid-liquid phase transfer catalysis", XP002153085, retrieved from STN Database accession no. 116:151263
DATABASE CHEMABS [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; CHEN, JICHOU ET AL: "Synthesis of carboxyphenoxyacetic acid derivatives using liquid-liquid phase transfer catalysis", XP002153085, retrieved from STN Database accession no. 116:151263
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