Title:
SUBSTITUTED PICOLINAMIDE COMPOUND AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2017/133423
Kind Code:
A1
Abstract:
A substituted picolinamide compound and use thereof. In particular, a deuterium substituted picolinamide compound represented by formula (I) and a pharmaceutical composition comprising the compound or a crystal form, a pharmaceutically acceptable salt, a prodrug, a stereisomer, a hydrate or a solvate of the same are disclosed. The compound can be used as a JAK inhibitor and can in turn be useful in the preparation of drugs for treating JAK-related diseases (e.g. autoimmune diseases and the like).
Inventors:
WANG YIHAN (CN)
REN XINGYE (CN)
REN XINGYE (CN)
Application Number:
PCT/CN2017/071128
Publication Date:
August 10, 2017
Filing Date:
January 13, 2017
Export Citation:
Assignee:
SHENZHEN TARGETRX INC (CN)
International Classes:
C07D471/04; A61K31/437; A61P19/02; C07D487/04
Domestic Patent References:
| WO2016179207A1 | 2016-11-10 |
Foreign References:
| CN102482273A | 2012-05-30 | |||
| CN104379173A | 2015-02-25 | |||
| CN102105471A | 2011-06-22 | |||
| CN105061420A | 2015-11-18 |
Download PDF: